DNA interaction analysis of fluorenylidene double bridged cyclotriphosphazene derivatives

DNA Binding Characteristics and Protective Effects of Yellow Pigment from Freshly Cut Yam (Dioscorea opposita)

“…Bathochromic effects were also observed in the visible absorption ( Figure 2), providing clear evidence for the binding between YP and ctDNA. Similarly, the binding of the novel 9-O-Naryl/aryl-alkyl amino carbonyl methyl to ctDNA [13] and the formation of complexes between DNA and fluorenylidene double-bridged cyclotriphosphazene derivatives [14] were found to contribute to the bathochromic shift of visible absorption, which thus supported the formation of DNA-YP complexes.…”

Synthesis, characterization and cytotoxic activity studies on cancer cell lines of new paraben-decorated monospiro-cyclotriphosphazenes

“…In general, the results of both studies were considered quite promising. 22,23 In a study conducted in 2018, the effects on the DNA structure of fully parabensubstituted fluorenylidene double-bridged cyclotriphosphazene compounds synthesized for the first time were investigated with a biosensor device that measures DNA hybridization efficiency on its biochip surface and carries out agarose gel electrophoresis 24 .…”

“…[16][17][18][19][20][21] Studies investigating the effects on DNA of paraben derivatives of cyclophosphazenes were carried out by our group. [22][23][24][25][26] In these studies, different new paraben derivative cyclotriphosphazene and cyclotetraphosphazene compounds were successfully synthesized and the DNA effects of these compounds as potential drug candidates were investigated. Generally, the results obtained from the studies were considered to be highly promising.…”

Chemosensor properties of 7-hydroxycoumarin substituted cyclotriphosphazenes

“…Depending on the attached groups, they are suitable for the synthesis of different compounds for various applications [19,20]. During the past two decades, nucleophilic substitution reactions at phosphorus atoms of hexachlorocyclotriphosphazene have been extensively explored, leading to an enormous variety of materials with interesting properties such as anticancer [21] and antimicrobial agents [22] or fluorescence sensors [23]. Although there are many studies about coumarin, there are few studies about cyclotriphosphazenes bearing coumarin groups.…”