DNA-functionalization gold nanoparticles based fluorescence sensor for sensitive detection of Hg2+ in aqueous solution

Wang, Gongke; Lu, Yanfang; Yan, Changling; Lu, Yan

doi:10.1016/j.snb.2015.01.051

Cited by 64 publications

(27 citation statements)

References 35 publications

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“…For instance, T–Hg 2+ –T complex-induced conformational change of ssDNA allows one-step sensing of Hg 2+ in a AuNPs-based sensor developed by G. Wang et al [119]. The AuNPs were used as acceptor and FAM as donor.…”

Section: Biosensing Methodsmentioning

confidence: 99%

Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis

et al. 2019

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: Microsystems and biomolecules integration as well multiplexing determinations are key aspects of sensing devices in the field of heavy metal contamination monitoring. The present review collects the most relevant information about optical biosensors development in the last decade. Focus is put on analytical characteristics and applications that are dependent on: (i) Signal transduction method (luminescence, colorimetry, evanescent wave (EW), surface-enhanced Raman spectroscopy (SERS), Förster resonance energy transfer (FRET), surface plasmon resonance (SPR)); (ii) biorecognition molecules employed (proteins, nucleic acids, aptamers, and enzymes). The biosensing systems applied (or applicable) to water and milk samples will be considered for a comparative analysis, with an emphasis on water as the primary source of possible contamination along the food chain.

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Section: Biosensing Methodsmentioning

confidence: 99%

Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis

et al. 2019

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“…This phenomenon involving metal nanoparticles functionalized to a fluorophore can be exploited to detect environmental pollutions [ 60 , 61 , 62 , 63 , 64 , 65 ]. It is possible to identify two sensor classes.…”

Section: Physical Aspects Behind Fluorescence Response To Environmmentioning

confidence: 99%

Metal Nanostructures for Environmental Pollutant Detection Based on Fluorescence

Burratti

Ciotta

et al. 2021

Nanomaterials

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Heavy metal ions and pesticides are extremely dangerous for human health and environment and an accurate detection is an essential step to monitor their levels in water. The standard and most used methods for detecting these pollutants are sophisticated and expensive analytical techniques. However, recent technological advancements have allowed the development of alternative techniques based on optical properties of noble metal nanomaterials, which provide many advantages such as ultrasensitive detection, fast turnover, simple protocols, in situ sampling, on-site capability and reduced cost. This paper provides a review of the most common photo-physical effects impact on the fluorescence of metal nanomaterials and how these processes can be exploited for the detection of pollutant species. The final aim is to provide readers with an updated guide on fluorescent metallic nano-systems used as optical sensors of heavy metal ions and pesticides in water.

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“…Because of their unique optical properties they are widely used in both diagnostic and therapeutic systems [37]. AuNPs can easily form a covalent bond with thiol derivatives and can therefore become tightly anchored with some genetic fragments without any complex modification processes [38].…”

Section: Nanomaterials With Biological Relevancementioning

confidence: 99%

Regulation of cellular gene expression by nanomaterials

Chun

Yuk

2018

Nano Convergence

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Within a cell there are several mechanisms to regulate gene expression during cellular metabolism, growth, and differentiation. If these do not work properly, the cells will die or develop abnormally and, in some cases, even develop into tumors. Thus, a variety of exogenous and endogenous approaches have been developed that act on essential stages of transcription and translation by affecting the regulation of gene expression in an intended manner. To date, some anticancer strategies have focused on targeting abnormally overexpressed genes termed oncogenes, which have lost the ability to tune gene expression. With the rapid advent of nanotechnology, a few synthetic nanomaterials are being used as gene regulation systems. In many cases, these materials have been employed as nanocarriers to deliver key molecules such as silencing RNAs or antisense oligonucleotides into target cells, but some nanomaterials may be able to effectively modulate gene expression due to their characteristic properties, which include tunable physicochemical properties due to their malleable size and shape. This technology has improved the performance of existing approaches for regulating gene expression and led to the development of new types of advanced regulatory systems. In this short review, we will present some nanomaterials currently used in novel gene regulation systems, focusing on their basic features and practical applications. Based on these findings, it is further envisioned that next-generation gene expression regulation systems involving such nanomaterials will be developed.

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DNA-functionalization gold nanoparticles based fluorescence sensor for sensitive detection of Hg2+ in aqueous solution

Cited by 64 publications

References 35 publications

Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis

Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis

Metal Nanostructures for Environmental Pollutant Detection Based on Fluorescence

Regulation of cellular gene expression by nanomaterials

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