DNA fluorescence shift sensor: A rapid method for the detection of DNA hybridization using silver nanoclusters

Fluorescent silver nanocluster DNA probes for multiplexed detection using microfluidic capillary electrophoresis

“…12,13 The prospect of incorporating sequences for both AgNC stabilization and DNA target binding selectivity into a single oligomer has led to a growing number of novel detection strategies. 14 Some methods of DNA detection using AgNCs rely on spectral shifts, 15,16 while others produce 'turn-on' probes, [5][6][7] providing a simple and robust method for fluorescence based DNA detection.…”

Dengue serotyping with a label-free DNA sensor

“…36 Recent publications highlighting the incorporation of AgNCs in DNA detection have been attracting wide interest. DNA detection using AgNCs mostly relies on analysing AgNC spectra shis 37 or "turn-on/turn-off" strategies. 38,39 Here, we describe a DNA detection probe system for dengue serotyping utilizing AgNC formation aer target assisted isothermal exponential amplication (TAIEA).…”

A nanocluster beacon based on the template transformation of DNA-templated silver nanoclusters

“…Together with the convenient synthesis and the excellent properties, NCBs were widely used in the construction of sensing platforms for a lot of biomolecules. [12][13][14] For instance, Yeh et al developed a chameleon NCB for single-nucleotide polymorphism detection, which had a 60-70 nm emission shift dependent on the alignment between Ag NCs and G-rich sequences. 15 Nevertheless, the scarcity of flexible and effective methods for modulating the fluorescence of DNA-Ag NCs impedes the development of general biosensors based on DNA-Ag NCs.…”