DNA‐encoded plasmonic bubbles aggregating dual‐microRNA SERS signals for cancer diagnosis
Yu Yang,
Hao Lu,
Dan Fang
et al.
Abstract:Solid bubbles have expanded the SERS assay toolbox, but their detection performance in biofluids is still hampered by the irrational design of the plasmonic sensing interface. A plasmonic bubble aggregate‐driven DNA‐encoded SERS assay is reported here that enables simultaneous, ultrasensitive, and specific detection of multiple miRNAs in blood samples for accurate cancer diagnosis. In this assay, the buoyancy of plasmonic bubbles allows them to self‐aggregate at a droplet apex for SERS reconfiguration, form si… Show more
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