DNA–carbon nano onion aggregate: triangle, hexagon, six-petal flower to dead-end network

Babar, Dipak Gorakh; Pakhira, Bholanath; Sarkar, Sabyasachi

doi:10.1007/s13204-017-0570-2

Cited by 6 publications

(5 citation statements)

References 15 publications

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“… 19 , 20 Also the denaturation and deactivation of ds-DNA under similar light-induced interaction with CNO were reported. 24 Therefore, the mode of action of hydrogen peroxide to destroy SARS-CoV-2 may be envisioned as follows. The lipid layer of SARS-CoV-2 has several pockets to invite hydrogen bond interactions with hydrophilic CNO leading to adduct formation.…”

Section: Resultsmentioning

confidence: 99%

Sustained generation of peroxide from the air by carbon nano onion under visible light to combat RNA virus

2022

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Graphical abstract Carbon nano onion (CNO) from dried grass has been synthesized by carbonization in the size range, 20 to 100 nm. This shows catalytic property to transform aerial oxygen under visible light to generate reactive oxygen species (ROS). A concept has been presented herein to show that this CNO even under room light generates hydrogen peroxide which inhibits WSN influenza virus (H1N1). The advantage of introducing CNO, synthesized from a cheap source to cater to the global need, is to sterilize infected hospitals indoor and outdoor, aircraft carriers, air conditioner vents due to its sustained conversion of air to ROS. Thus, CNO use could prevent frequent evacuation as used by conventional sanitisers to sterilize infected places from other RNA virus and hospital pathogens under COVID-19 pandemic. Carbon nano onion (CNO) under aerial oxygen on exposure with visible light generates ROS which is capable to rupture the lipid envelope of SARS-CoV-2 followed by disintegrating its RNA.

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Section: Resultsmentioning

confidence: 99%

Sustained generation of peroxide from the air by carbon nano onion under visible light to combat RNA virus

2022

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“…49,75 The first supramolecular CNO-based system was reported 2008, by Echegoyen et al 76 Since then, non-covalent binding has become increasingly popular as a mode of moiety-attachment to the CNO surface. 29,49,50,[77][78][79][80][81][82][83][84][85][86] Moreover, in the recent years, an increasing interest has been observed in utilising non-covalent functionalisation for drug delivery related applications. 37,38 As the primary function of a nanocarrier is to deliver and release a drug payload at the target site, one must consider an appropriate approach for appending the drug onto the nanomaterial surface.…”

Section: Modification Of the Nanocarriermentioning

confidence: 99%

Carbon nano-onions as potential nanocarriers for drug delivery

Bartkowski

Giordani

2021

Dalton Trans.

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“…This dead-end network aggregate lacked the intrinsic optical property of DNA and displayed a loss of its activity (Figure 10). The researchers finally concluded that the wsCNO being non-toxic can be explored to control the unwanted proliferation of rouged DNA by interacting with wsCNO, which can be utilized for the prevention of such viral DNA replication in recognized diseases [200]. Tripathi et al developed graphitic photoluminescent water-soluble carbon nanoonions (wsCNO) from the traditional pyrolysis of vegetable ghee without employing any metal catalyst through a simple oxidative treatment using nitric acid.…”

Section: Carbon Nano-onions For Therapeutics Deliverymentioning

confidence: 99%

Carbon-Based Nanomaterials for Delivery of Biologicals and Therapeutics: A Cutting-Edge Technology

Mahor

Singh

Bharadwaj

et al. 2021

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After hydrogen and oxygen, carbon is the third most abundant component present in the cosmos with excellent characteristic features of binding to itself and nearly all elements. Since ancient times, carbon-based materials such as graphite, charcoal, and carbon black have been utilized for writing and drawing materials. As these materials possess excellent chemical, mechanical, electrical, and thermal features, they have been readily engineered into carbon-based nanomaterials (CNMs) such as carbon nanotubes, graphene oxide, graphene quantum dots, nanodiamonds, fullerenes, carbon nano-onions, and so forth. These materials are now widely explored in biomedical applications. Thus, the emergence of CNMs has opened up a gateway for the detection, delivery, and treatment of a multitude of diseases. They are being actively researched for applications within tissue engineering, as vaccine vectors, and for the delivery of therapeutics to the immune system. This review focuses on the recent advances in various types of CNMs, their fabrication techniques, and their application in the delivery of therapeutics both in vitro and in vivo. The review also focuses on the toxicity concern of the CNMs and the possible remedies to tackle the toxicity issues. Concluding remarks emphasize all the CNMs discussed in the review over their possible biomedical applications, while the future perspectives section discusses the approaches to bring CNMs into the mainstream of clinical trials and their therapeutic applications.

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DNA–carbon nano onion aggregate: triangle, hexagon, six-petal flower to dead-end network

Cited by 6 publications

References 15 publications

Sustained generation of peroxide from the air by carbon nano onion under visible light to combat RNA virus

Sustained generation of peroxide from the air by carbon nano onion under visible light to combat RNA virus

Carbon nano-onions as potential nanocarriers for drug delivery

Carbon-Based Nanomaterials for Delivery of Biologicals and Therapeutics: A Cutting-Edge Technology

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