2011
DOI: 10.1007/s12024-011-9276-z
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DNA analysis in disaster victim identification

Abstract: DNA profiling and matching is one of the primary methods to identify missing persons in a disaster, as defined by the Interpol Disaster Victim Identification Guide. The process to identify a victim by DNA includes: the collection of the best possible ante-mortem (AM) samples, the choice of post-mortem (PM) samples, DNA-analysis, matching and statistical weighting of the genetic relationship or match. Each disaster has its own scenario, and each scenario defines its own methods for identification of the decease… Show more

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Cited by 59 publications
(36 citation statements)
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“…As the female victim is a Kyrgyzstan national, there was some issues with the embassy and to obtain the first degree relatives blood. To overcome this issue, another option for AM DNA samples recommended by INTERPOL is the personal objects used by the deceased [3]. Profiles generated from personal objects can be directly compared to the DNAprofiles of victims.…”
Section: Discussionmentioning
confidence: 99%
“…As the female victim is a Kyrgyzstan national, there was some issues with the embassy and to obtain the first degree relatives blood. To overcome this issue, another option for AM DNA samples recommended by INTERPOL is the personal objects used by the deceased [3]. Profiles generated from personal objects can be directly compared to the DNAprofiles of victims.…”
Section: Discussionmentioning
confidence: 99%
“…direct profile matching. This may necessitate sampling from sources including tooth brushes, razors, brushes, combs, hats, underwear and dental appliances where it is known that the missing person's DNA is most likely to be located (Montelius and Lindblom 2012). To avoid erroneous DNA mixtures, the expert has to ensure that the items can only have been used by the missing person and cross checking between these different sources will ensure that a robust profile is secured.…”
Section: Primary Methods Of Identificationmentioning
confidence: 99%
“…Here we expand on victim identification, making the simplifying assumption that there is no commingling of remains so that we are solely attempting to make identifications. Rather than working directly with posterior probabilities as in the previous section, we will work with likelihood ratios and prior odds as this is much more common in the disaster victim and personal identification literature (Goodwin et al, 1999;Adams, 2003b;Brenner and Weir, 2003;Alonso et al, 2005;Christensen, 2005;Lin et al, 2006;Steadman et al, 2006;Prinz et al, 2007;Kaye, 2009;Budowle et al, 2011;Butler, 2011;Hartman et al, 2011;Abraham et al, 2012;Montelius and Lindblom, 2012;Jackson and Black, 2013). As mentioned above, likelihood ratios from DNA are typically reported as the inverse of the population frequency for the matched (between ante-mortem and post-mortem) genotype, although this is only possible when a "direct reference" ante-mortem sample is available (so that the numerator is equal to 1.0).…”
Section: Identification In a "Closed Population" Mass Disastermentioning
confidence: 99%