DL-DDA - Deep Learning based Dynamic Difficulty Adjustment with UX and Gameplay constraints

Or, Dvir Ben; Kolomenkin, Michael; Shabat, Gil

doi:10.1109/cog52621.2021.9619162

Cited by 8 publications

(2 citation statements)

References 14 publications

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“…The cationic surfactant DDA, in comparison to other liposomes, was distinguished as the most efficient tool in terms of antibody production and also the amount of IFN‐γ induced. In spite of the use of DDA as an adjuvant for a long time, 59 humans have been given the drug 78 . However, its exact role as an adjuvant is still unclear.…”

Section: Liposomal Subunit Vaccines Against Tbmentioning

confidence: 99%

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Liposomal delivery system/adjuvant for tuberculosis vaccine

Moradi

Vahedi

Abbassioun

et al. 2023

Immunity Inflam & Disease

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As reported by the World Health Organization, about 10 million individuals were infected with tuberculosis (TB) worldwide. Moreover, approximately 1.5 million people died of TB, of which 214,000 were infected with HIV simultaneously. Due to the high infection rate, the need for effective TB vaccination is highly felt. Until now, various methodologies have been proposed for the development of a protein subunit vaccine for TB. These vaccines have shown higher protection than other vaccines, particularly the Bacillus culture vaccine. The delivery system and safety regulator are common characteristics of effective adjuvants in TB vaccines and the clinical trial stage.The present study investigates the current state of TB adjuvant research focusing on the liposomal adjuvant system. Based on our findings, the liposomal system is a safe and efficient adjuvant from nanosize to microsize for vaccinations against TB, other intracellular infections, and malignancies. Clinical studies can provide valuable feedback for developing novel TB adjuvants, which ultimately enhance the impact of adjuvants on next-generation TB vaccines.

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Section: Liposomal Subunit Vaccines Against Tbmentioning

confidence: 99%

“…In spite of the use of DDA as an adjuvant for a long time, 59 humans have been given the drug. 78 However, its exact role as an adjuvant is still unclear. It has been proven that DDA is a very beneficial gene uptake facilitator in the transfection field.…”

Section: Liposomal Subunit Vaccines Against Tbmentioning

confidence: 99%