“…However, whereas joint hypermobility syndrome and EDS display a high prevalence of functional GI disorders, in MFS, the prevalence of GI disorders is still disputed [ 13 , 14 , 24 , 25 ]. To date, GI disease associated with MFS has been reported only in case series, highlighting, in particular, its association with complications of intestinal diverticula, a condition for which MFS is historically considered a genetic risk factor [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ]. Furthermore, the level of evidence supporting the relationship between MFS and diverticulosis, and its potentially related symptoms, is still unsatisfactory.…”