“…The presentation of severe DB varies from brisk large-volume hematochezia to intermittent dark-red stool [5]. The presentation of large-volume hematochezia in the setting of appropriate age group or known prior history of diverticulosis carries a high pre-test probability of DB as a cause of gastrointestinal bleeding.…”
Background
Diverticular bleeding (DB) is the most common cause of severe acute lower gastrointestinal bleeding (GIB) in developed countries. The role of early colonoscopy (
<
24 hours) continues to remain controversial and data on early colonoscopy in acute DB are scant. We aimed to evaluate the effect of timing of colonoscopy on outcomes in patients with acute DB using a nationwide inpatient sample.
Methods
Data from the nationwide inpatient sample from 2012 to 2014 were used. The ninth version of the International Classification of Diseases coding system ICD 9 was used for patient selection. We included discharges with the primary and secondary inpatient diagnosis of diverticulosis with bleeding and diverticulitis with bleeding. Discharges with no primary or secondary diagnosis of diverticulosis with bleeding, diverticulitis with bleeding, patients who were less than 18 years old and those who did not undergo colonoscopy during the admission were excluded. The primary outcomes were length of stay (LOS) and total hospitalization costs.
Results
A total of 88 600 patients were included in our analysis, amongst whom 45 020 (50.8%) had colonoscopy within 24 hours of admission (early colonoscopy), while 43 580 (49.2%) patients had colonoscopy after 24 hours of admission (late colonoscopy). LOS was significantly lower in patients with early colonoscopy as compared to those with late colonoscopy (3.7 vs 5.6 days,
P
< 0.0001). Total hospitalization costs were also significantly lower in patients with early colonoscopy ($9317 vs $11 767,
P
< 0.0001). There was no difference in mortality between both groups (0.7 vs 0.8%). After adjusting for potential confounders, the differences in LOS and total hospitalization costs between early and late colonoscopy remained statistically significant.
Conclusions
Early colonoscopy in acute DB significantly reduced LOS and total hospitalization costs. There was no significant difference in mortality observed. Performance of early colonoscopy in the appropriate patients presenting with acute DB can have potential cost-saving implications. Further research is needed to identify which patients would benefit from early colonoscopy in DB.
“…The presentation of severe DB varies from brisk large-volume hematochezia to intermittent dark-red stool [5]. The presentation of large-volume hematochezia in the setting of appropriate age group or known prior history of diverticulosis carries a high pre-test probability of DB as a cause of gastrointestinal bleeding.…”
Background
Diverticular bleeding (DB) is the most common cause of severe acute lower gastrointestinal bleeding (GIB) in developed countries. The role of early colonoscopy (
<
24 hours) continues to remain controversial and data on early colonoscopy in acute DB are scant. We aimed to evaluate the effect of timing of colonoscopy on outcomes in patients with acute DB using a nationwide inpatient sample.
Methods
Data from the nationwide inpatient sample from 2012 to 2014 were used. The ninth version of the International Classification of Diseases coding system ICD 9 was used for patient selection. We included discharges with the primary and secondary inpatient diagnosis of diverticulosis with bleeding and diverticulitis with bleeding. Discharges with no primary or secondary diagnosis of diverticulosis with bleeding, diverticulitis with bleeding, patients who were less than 18 years old and those who did not undergo colonoscopy during the admission were excluded. The primary outcomes were length of stay (LOS) and total hospitalization costs.
Results
A total of 88 600 patients were included in our analysis, amongst whom 45 020 (50.8%) had colonoscopy within 24 hours of admission (early colonoscopy), while 43 580 (49.2%) patients had colonoscopy after 24 hours of admission (late colonoscopy). LOS was significantly lower in patients with early colonoscopy as compared to those with late colonoscopy (3.7 vs 5.6 days,
P
< 0.0001). Total hospitalization costs were also significantly lower in patients with early colonoscopy ($9317 vs $11 767,
P
< 0.0001). There was no difference in mortality between both groups (0.7 vs 0.8%). After adjusting for potential confounders, the differences in LOS and total hospitalization costs between early and late colonoscopy remained statistically significant.
Conclusions
Early colonoscopy in acute DB significantly reduced LOS and total hospitalization costs. There was no significant difference in mortality observed. Performance of early colonoscopy in the appropriate patients presenting with acute DB can have potential cost-saving implications. Further research is needed to identify which patients would benefit from early colonoscopy in DB.
“…GD is thought to develop within the gastrointestinal wall due to the development of abnormal pressure within the organs, defects in the bowel wall or dysfunctional peristalsis 6 …”
A 7‐year 9‐month‐old, neutered, male British shorthair cat was referred for chronic regurgitation and vomiting. Previous symptomatic medical management did not improve these clinical signs. Survey radiographs and abdominal ultrasound revealed no significant abnormalities of the gastrointestinal tract. Exploratory laparotomy was performed to obtain gastrointestinal biopsies. Sliding hiatal hernia and an abnormal gastric outpouching at the fundus, measuring 15 × 15 × 15 mm, were identified. Surgical treatment of the hiatal hernia included phrenoplasty, oesophagopexy and left‐sided gastropexy. Additionally, the gastric outpouching was resected. Histopathologic examination of the excised fundic tissue revealed findings consistent with those indicative of a false gastric diverticulum. Postoperative examinations on Days 5 and 10 and telephone follow‐up on Days 30 and 120 revealed a marked reduction in clinical signs. The combination of surgical techniques—phrenoplasty, left‐sided gastropexy, oesophagopexy and gastric diverticulum resection—was found to effectively improve the cat's clinical signs.
“…A diverticulum can develop throughout the gastrointestinal tract and takes the form a pouch structure projecting outward from the canal that may contain one or more of the gastrointestinal tract layers 1 . The purpose of this report is to discuss diverticular formation in the stomach, which is rare 2 and the least common type of gastrointestinal diverticula 3 .…”
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