Diverticular disease of the colon: a deficiency disease of Western civilization.

Painter, Neil S.; Burkitt, Denis

doi:10.1136/bmj.2.5759.450

Cited by 798 publications

(376 citation statements)

References 17 publications

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“…The interval of 20 years or so may suggest the latent period of colon diverticula. This interval is much shorter than 40 years reported by Painter and Burkitt (1971).…”

Section: Discussionmentioning

confidence: 58%

Epidemiological Evaluation of Colonic Diverticulosis and Dietary Fiber in Japan

Munakata

Nakaji

Takami

et al. 1993

Tohoku J. Exp. Med.

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“…The interval of 20 years or so may suggest the latent period of colon diverticula. This interval is much shorter than 40 years reported by Painter and Burkitt (1971).…”

Section: Discussionmentioning

confidence: 58%

Epidemiological Evaluation of Colonic Diverticulosis and Dietary Fiber in Japan

Munakata

Nakaji

Takami

et al. 1993

Tohoku J. Exp. Med.

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“…These diverticula may become inflamed, may bleed and, in complicated cases, form abscesses, fistula, cause bowel obstruction, peritonitis and septicaemia. Diverticular disease was one of the first conditions that Painter & Burkitt (64) highlighted in the 1970s as being potentially linked to low dietary fibre consumption. A relatively small number of cohort studies have subsequently explored the relationship between dietary fibre intakes and risk of diverticular disease; these have consistently found evidence of a lower incidence with higher total fibre consumption (65)(66)(67) .…”

Section: Gastrointestinal Healthmentioning

confidence: 99%

Dietary fibre in Europe: current state of knowledge on definitions, sources, recommendations, intakes and relationships to health

Stephen

Champ

Cloran³

et al. 2017

Nutr. Res. Rev.

544

483

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Research into the analysis, physical properties and health effects of dietary fibre has continued steadily over the last 40-50 years. From the knowledge gained, countries have developed guidelines for their populations on the optimal amount of fibre to be consumed each day. Food composition tables from many countries now contain values for the dietary fibre content of foods, and, from these, combined with dietary surveys, population intakes have been determined. The present review assessed the uniformity of the analytical methods used, health claims permitted, recommendations and intakes, particularly from national surveys across Europe and around the world. It also assessed current knowledge on health effects of dietary fibre and related the impact of different fibre types on health. The overall intent was to be able to provide more detailed guidance on the types of fibre which should be consumed for good health, rather than simply a total intake figure, the current situation. Analysis of data indicated a fair degree of uniformity in the definition of dietary fibre, the method used for analysis, the recommended amount to be consumed and a growing literature on effects on digestive health and disease risk. However, national dietary survey data showed that intakes do not reach recommendations and very few countries provide guidance on the types of fibre that are preferable to achieve recommended intakes. Research gaps were identified and ideas suggested to provide information for more detailed advice to the public about specific food sources that should be consumed to achieve health benefits.

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“…Dietary fiber is assumed to shorten large intestine transit time, soften feces, increase fecal volume, and suppress the elevation of the internal pressure of the large intestine (Painter and Burkitt 1971). Alternatively, accumulation of fat in the serous membrane layer, particularly in the sites perforated by blood vessels, which are the most common sites of diverticula, is believed to increase the fragility of the intestinal wall (Shinohara 1955).…”

Section: Fat Absorptionmentioning

confidence: 99%

Effects of Dietary Fiber on Gastrointestinal Transit Time, Fecal Properties and Fat Absorption in Rats.

Munakata¹,

Iwane²,

Todate³

et al. 1995

Tohoku J. Exp. Med.

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The gastrointestinal transit time of food was determined by x-ray fluoroscopy using barium sulfate in rats fed with diets of various dietary fiber contents, and the effects of dietary fiber on the transit time, properties of feces, and fat absorption were examined. In 4-and 16-month-old rats fed with the diet for 3 and 15 month, respectively, the transit time of the cecum and colon in those receiving 20 and 40% wheat bran diets was shortened compared with that in the 0% group. The fecal pellet number and volume increased as the wheat bran content of the diet increased. In another experiments, the daily total fat excretion was found to be the greatest in rats receiving 15% pectin diet, followed by rats receiving 15% cellulose and non-fiber diets, respectively. These results suggest that shortening of the transit time through the cecum and colon with increase of fecal volume and suppression of fat absorption all participate in the mechanism of the inhibitory action of wheat bran on carcinogenesis and on the development of diverticulum of the large intestine, dietary fiber; wheat bran; transit timeThe effects of dietary fiber (DF) on gastrointestinal function, which have been described in many reports, include its action in shortening the gastrointestinal transit time of food, especially large intestine transit time, which has received attention as a major factor for the development of colonic carcinomas, and also for the development of diverticulum in the large intestine (Burkitt 1971;Burkitt et al. 1972). In the present study, we measured the transit time of food through each of the esophagus, stomach, and small and large intestine in rats fed with wheat bran by x-ray fluoroscopy using barium sulfate to examine the effects of dosage and administration period of wheat bran on the transit time. The changes in fecal properties induced by wheat bran administration and the effects of pectin

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Diverticular disease of the colon: a deficiency disease of Western civilization.

Cited by 798 publications

References 17 publications

Epidemiological Evaluation of Colonic Diverticulosis and Dietary Fiber in Japan

Epidemiological Evaluation of Colonic Diverticulosis and Dietary Fiber in Japan

Dietary fibre in Europe: current state of knowledge on definitions, sources, recommendations, intakes and relationships to health

Effects of Dietary Fiber on Gastrointestinal Transit Time, Fecal Properties and Fat Absorption in Rats.

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