Despite the alarming symptoms of perforated duodenal diverticula, they are sometimes diagnosed late or even overlooked, reflecting a 13% mortality rate in recent decades. Between 1980 and 1989 8 patients with perforated duodenal diverticula who had had abdominal symptoms for 1 h to 3 days prior to admission with acute and gradual onset in 5 and 3 of them, respectively, were diagnosed and treated in our department. Six patients (4 women and 2 men; age range 61-81 years) were operated on without any mortality 3 (n = 3), 8 (n = 1), and 16 (n = 1) h after admission, but 2 of these were reexplored 1 and 5 days later, respectively, because the perforation was overlooked initially. The 6th patient had surgery 13 days after admission when a retroduodenal abscess was revealed, the origin of which was a perforated duodenal diverticulum. A 73-year-old woman was treated conservatively, and 1 51-year-old man had a diverticulum perforation and subsequent surgery during the postoperative period after a raphe procedure for perforated duodenal ulcer. Two patients had postoperative cardiopulmonary failure and were kept mechanically ventilated for 3 and 4 weeks, respectively. The patient subjected to delayed surgery had a complicated postoperative course but has recovered fully. The last patient with numerous reoperations, intensive care with assisted ventilation for 3 months, and anuria for 5 months has recovered except for an incisional hernia and chronic abdominal pain. The hospital stay was 9 and 12 days and 2, 5, 5, and 13 weeks in 6 patients, respectively, and 13 months in 1 patient. The conservatively treated patient was discharged after 3 weeks.