Diversity of bacterial and fungal endophytic communities presents in the leaf blades of Sinningia magnifica, Sinningia schiffneri and Sinningia speciosa from different cladus of Gesneriaceae family: A comparative analysis in three consecutive years

Antitumoral photoinduced effects of crude extract, fractions, and naphthoquinones from Sinningia magnifica (Otto & A. Dietr.) Wiehler (Gesneriaceae) in a bioguided study

“…[5][6][7][8][9] At least 75 species of herbs comprise the Sinningia genus, most of them native to Brazil. [8][9][10][11][12] The species of Gesneriaceae are traditionally used for respiratory problems, wounds, fever, inflammation, pain, snake bites, and infectious diseases. 10,12,13,14,15,16 Phytochemical research on Sinninigia species has mainly reported the identification of terpenes, phenolic glycosides, and compounds from the quinone class, some with documented biological activities such as antioxidant, anti-inflammatory properties, and cytotoxic activity for cancer cell lines.…”

“…Wiehler is a rupicolous species often found growing in rock crevices in highland grasslands of the Brazilian tropical forests, as well as it has been cultivated in vitro, in plants and calli forms, displaying potent antioxidant capacity and the ability to produce secondary metabolites in large quantities. 11,21 Photodynamic therapy (PDT) has aroused growing interest as a therapeutic alternative in some types of cancer, as it is a noninvasive, selective therapy, that can accurately target early diagnosed tumors, has moderate or minimal side effects, does not cause harm to healthy tissue, and improves the quality and longevity of patients in advanced stages of the disease. [23][24][25][26][27] This therapy is based on the administration of a light sensitive (photosensitizer), either systemically or topically substance, followed by low-dose irradiation with visible light of a suitable wavelength.…”