Diversity of allergens causing occupational asthma among cereal workers as demonstrated by exposure procedures

“…In addition, other professions, particularly in the food industry, like poultry and ham workers, can also develop sensitization and respiratory symptoms due to storage mites [163]. IgE-mediated allergy to storage mites has been demonstrated by skin prick testing and measurements of allergen-specific IgE, and confirmed by specific inhalation challenges [164, 165]. The occurrence of nasal symptoms has been found to precede the development of lower airway symptoms [160].…”

Section: Clinical Pictures: Asthma Rhinitis/rhinosinusitis Atopic Dmentioning

confidence: 99%

International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem

Sánchez‐Borges

Fernández-Caldas

Thomas

et al. 2017

World Allergy Organization Journal

View full text Add to dashboard Cite

Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), the European Academy of Allergy and Clinical Immunology (EAACI), and the World Allergy Organization (WAO), has proposed to issue an International Consensus (ICON) on the clinical consequences of mite hypersensitivity. The objectives of this document are to highlight aspects of mite biology that are clinically relevant, to update the current knowledge on mite allergens, routes of sensitization, the genetics of IgE responses to mites, the epidemiologic aspects of mite hypersensitivity, the clinical pictures induced by mites, the diagnosis, specific immunotherapeutic approaches, and prevention.

show abstract

“…Nine proteins were recognised, with molecular weights ranging from 54.5 to 14.9 kDa (15). Reactivity to soybean flour was also observed in a study performed by Alvarez et al (24) in 9 of 21 cereal workers. Therefore, the allergens involved in occupational asthma may differ from the causative agents in the Barcelona epidemics.…”

Section: Occupational Asthma Allergensmentioning

confidence: 49%