Diversity in Clinical Pharmacology and Therapeutics

Diversity, Equity, and Inclusion: Translating Clinical Pharmacology for All

“…The prospective and purposeful enablement of diversity, equity, and inclusion (DEI) is a critical core competency for today's multidisciplinary continuum of clinical pharmacology and translational science. Clinical Pharmacology and Therapeutics ( CPT ) has adopted DEI as core guiding principles in our field 1,2 . Building upon CPT 's mini‐themes on the topic in October 2021 1 and August 2022 2 and based on positive feedback from our readers and authors, the current issue was designed to showcase the core role of clinical pharmacology in elucidating and harnessing diversity in disease biology and pharmacologic response to enable safe and effective use of therapeutic innovations in all patients ( Figure ).…”

“…Clinical Pharmacology and Therapeutics ( CPT ) has adopted DEI as core guiding principles in our field 1,2 . Building upon CPT 's mini‐themes on the topic in October 2021 1 and August 2022 2 and based on positive feedback from our readers and authors, the current issue was designed to showcase the core role of clinical pharmacology in elucidating and harnessing diversity in disease biology and pharmacologic response to enable safe and effective use of therapeutic innovations in all patients ( Figure ). In this special issue, we highlight the need to enhance diversity and inclusion throughout the clinical development process, including racial and ethnic diversity and diversity in geographical location, disease diagnosis, and demographic factors such as age and gender.…”

Diversity in Clinical Pharmacology Coming of Age

“…In the Editorial of the October 2021 issue of Clinical Pharmacology & Therapeutics ( CPT ), it was proposed that “if diversity is defined as the inclusion of a range of many people that are different from each other, then it is obviously a core principle guiding best practices in clinical pharmacology and the foundation for personalized medicine and precision dosing.” 1 …”

“…Diversity spans at least four main dimensions in clinical pharmacology: gender/biological sex, ethnicity/race, specific populations, and age 1 . The latter is the topic of a series of articles in the current issue of CPT , which covers therapeutic treatment and evaluation in patient groups across the full age range, from preterm infants to geriatrics ( Figure ) 2–6 …”

Themes in Clinical Pharmacology and Therapeutics

“…The advantage of this format is that it gives the journal more flexibility to respond to emerging topics in an agile and timely manner. We published 4 such mini‐themes in 2021 9–12 ( Table 1 ) and are planning to build on their success and positive reception by our readers and authors in the coming years.…”