“…This collection of 11 papers attempts to put this quiet maturation in archaeal molecular biology in context with a mix of overview articles (Atomi et al, 2012; Hileman and Santangelo, 2012; Kohler and Metcalf, 2012; Wagner et al, 2012) and original data (Bernick et al, 2012a,b; Iverson and Stedman, 2012; Mao and Grogan, 2012; Schut et al, 2012; Stroud et al, 2012; Szabo and Pohlschroder, 2012) highlighting the expansion of important areas enabled by the 3G's: genomics, genetics, and global collaboration. Research papers highlight the roles of small RNAs, CRISPR action, mechanisms of membrane secretion, hydrogen production, and DNA replication, while excellent technical overviews cover recently developed genetic methods within four major research communities utilizing Haloferax, Sulfolobus, Pyrococcus, or Thermococcus.…”