Diverse Synthesis of (Thio)ethers and (Thio)esters Using Halodiborylmethane as a Transformable C1 Building Block
Chiwon Hwang,
Yunhui Jang,
Yongsuk Jung
et al.
Abstract:The development of effective strategies to forge C–O
and
C–S bonds in diverse chemical spaces is of considerable interest
in synthetic organic chemistry. Herein we report a versatile approach
for the modular synthesis of structurally diverse (thio)ethers and
(thio)esters via homologative coupling of α-halodiborylmethane
followed by transformation of the introduced diborylmethyl group.
This method accommodates a wide array of oxygen- and sulfur-containing
molecules, including biologically active compounds. The … Show more
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