Diverse physiological roles of the MqsR/MqsA toxin/antitoxin system
Viviana Sanchez-Torres,
Joy Kirigo,
Thomas K Wood
Abstract:There is tremendous interest in the use of bacteriophages (phages) to combat multi-drug resistant bacteria. However, to implement successfully phage therapy, host defense systems must be understood. Toxin/antitoxins (TAs) are the most prevalent phage defense system, and the MqsR/MqsA TA system is one of the best-studied systems; this phage-defense system was discovered in a whole-cell, population-averaged, transcriptome study designed to elucidate the biofilm-related genes of Escherichia coli in 2004; biofilms… Show more
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