Divalent metal ion catalysis in the hydrolysis of phosphomonoesters. Hydrolysis of 2-(1,10-phenanthrolyl) phosphate

Metallomicellar catalysis: Hydrolysis of phosphate monoester and phosphodiester by Cu(II), Zn(II) complexes of pyridyl ligands in CTAB micellar solution

“…In fact, the catalytic activity and mechanism of the coordinated and the hydrated metal ions have many similarities [14,15]; e.g., the higher pK a [16] of the hydrated Zn(II) leads to the greater activity of its metallomicelles for the hydrolysis compared with Cu(II). However, at lower pH, the contrary seems to be true; i.e., Cu (II) metallomicelles are more active for hydrolysis than Zn(II).…”

Metal Ion Catalysis in the Hydrolysis of Esters of 2-Hydroxy-1,10-phenanthroline: The Effects of Metal Ions on Intramolecular Carboxyl Group Participation

“…2-Hydroxy-1,10-phenanthroline was prepared by the synthetic scheme previously outlined (35) and was recrystallized from a benzene-ethanol mixture, mp 159-160 ЊC; lit. (35), mp 159-160 ЊC.…”

“…2-Hydroxy-1,10-phenanthroline was prepared by the synthetic scheme previously outlined (35) and was recrystallized from a benzene-ethanol mixture, mp 159-160 ЊC; lit. (35), mp 159-160 ЊC. The synthesis of the esters III and IV was carried out by dissolving freshly prepared 2-hydroxy-1,10-phenanthroline in tetrahydrofuran that had been distilled and dried.…”

Phosphate monoester hydrolysis at tricopper site: The advantage and disadvantage of closely assembled trimetallic active sites

“…Isolation and structural characterization of the hydrolysis product revealed that the produced inorganic phosphate was trapped in 1 and was also monoprotonated (see Section 3.3), a result further confirming the formulation of a {Cu 3 (HPO 4 )} core in ligand L1. However, in strong basic solutions, the HPO 4 2− group in 1 might deprotonate to give PO 4 3− [78], which results in an enhanced binding of the phosphate group at the tricopper site largely due to its increased negative charge and thus electron density (i.e., -donating property). As a result, the catalysis is self-inhibited due to the difficulty in releasing inorganic phosphate.…”