Diuretics, mortality, and nonrecovery of renal function in acute renal failure

Progression and outcomes of non‐dialysis dependent chronic kidney disease patients: A single center longitudinal follow‐up study

“…40,47 Increase phosphate level causes precipitation of calcium and phosphate in renal interstitium leading to interstitial fibrosis and tubular atrophy. 46 Patients using diuretics were [49][50][51] At baseline advance age, low eGFR, DM, low systolic blood pressure and low hemoglobin increased risk of mortality while being female decreased mortality risk in our cohort of patients. These findings are consistent with other large observational studies conducted in hospital settings.…”

Fluid management and diuretic therapy in acute renal failure

“…Uchino et al (2004) also conducted a study to determine the impact of diuretics on the mortality rate of critically ill patients with ARF. Their findings did not support those of Mehta et al (2002), concluding that diuretics are commonly prescribed in critically ill patients with ARF, and their use is not associated with higher mortality.…”

“…Administration of frusemide can therefore be effective in the management of hyperkalaemia (Mirpuri and Patel, 2000). Mehta et al (2002) conducted a study to determine whether the use of diuretics is associated with adverse or favourable outcomes in critically ill patients with ARF. It was concluded that the use of diuretics in critically ill patients with ARF was associated with an increased risk of death and non-recovery of renal function.…”

“…It was concluded that the use of diuretics in critically ill patients with ARF was associated with an increased risk of death and non-recovery of renal function. They also suggested that in the absence of compelling contradictory data from a randomized, blinded clinical trial, the widespread use of diuretic in critically ill patients with ARF should be discouraged (Mehta et al, 2002). Uchino et al (2004) also conducted a study to determine the impact of diuretics on the mortality rate of critically ill patients with ARF.…”

A nurse‐led intervention improves detection and management of AKI in Malawi

“…Acute kidney injury (AKI) is common in the developed world with more than 5% of general hospital admissions (Selby et al 2012) and 50% of critically ill patients experiencing an episode of AKI (Ostermann & Chang 2007). AKI, even in its mildest form, has a significant impact on survival and the development of long-term chronic kidney disease (CKD) (Mehta et al 2002;Amdur et al 2009;Ishani et al 2009;Lo et al 2009). Consequently, there is a major international campaign to improve the prevention, recognition, treatment and outcome of AKI (International Society of Nephrology 2014).…”