Dithiocarbamic Acid and Derivatives

Abstract

The article contains sections titled: 1. Introduction 2. Physical and Chemical Properties 3. Manufacture of Dithiocarbamate Salts 4. Transformation Products 4.1. Thiuram Sulfides 4.1.1. Thiuram Disulfides 4.1.2. Thiuram Monosulfides 4.1.3. Thiuram Trisulfides and Tetrasulfides 4.2. Thiocarbamoylsulfenamides 4.3. Thiocarbamoyl Chlorides 4.4. Dithiocarbamic Acid Esters 4.5. Heterocyclic Compounds 4.6. Other Derivatives 4.6.1. Dithiolanylium Salts 4.6.2. Alkylthioformimidic Chlorides 4.6.3. Isothiocyanates, Isocyanates, and Thioureas 4.7. Photolysis of Dithiocarbamates 5. Uses 5.1. Vulcanization Accelerators 5.2. Pesticides 5.3. Medical Applications 5.4. Radioprotective Agents 5.5. Imaging Technology 5.6. Other Uses 6. Toxicology and Occupational Health

Mechanistic Insight into the Photocontrolled Cationic Polymerization of Vinyl Ethers

“…Thiuram disulfides are commonly used as CTAs for radical RAFT polymerization and as reagents for the vulcanization of rubber . Notably, when substituted for CTA 2a , disulfide 7 affords no control over the polymerization (Table S7), a result that agrees with the proposed cationic process.…”

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

“…This can be explained by the increase in partial positive charge on the sulfur in sulfinic acid, which converts the sulfur atom into a harder electrophile making it less prone to reaction with soft nucleophiles, such as thiols. With a p K a of 2 , sulfinic acid is deprotonated at physiologic pH and can exist in two resonance forms (Chart ) . Sulfinic acids function as nucleophiles (Chart ), reacting largely from sulfur to undergo alkylation ( 27 ), as well as nucleophilic addition to activated alkenes ( 28 ), aldehydes ( 29 ), lactones ( 30 ), α,β-unsaturated compounds ( 31 ), and diazonium salts ( 32 ) to give the corresponding sulfones. , The preceding reactions are established for sulfinic acids under synthetic organic conditions, but it is not established whether all of these reactions would take place with protein sulfinic acids.…”

Synthesis, Characterization and <i>In-Vitro</i> Antimicrobial Studies of M<sup>2+</sup>+ Complexes of <i>p</i>-Chlorophenyl-, <i>p</i>-Bromophenyl-Dithiocarbamates

“…Dithiocarbamate is a group of organic compound, an analogue of carbamates in which both oxygen atoms are replaced by sulphur atoms [1]. The transition metal complexes (TMCs) of dithiocarbamates have been reported and applied in different areas of material science [2] [3] [4].…”