“…Diterpenoids are the main constituents in plants of the genus Euphorbia ( Xu Y. et al, 2021 ). More than 450 diterpenoids have been isolated from Euphorbia species ( Xu Y. et al, 2021 ), which are considered to be taxonomic markers of this genus ( Min et al, 2021 ). Diterpenoids from E. nematocypha have shown anticancer activity and antiproliferative effects against cell lines (HL-60, A549, MCF-7, HeLa, and P388), as well as antivirus, anti-inflammatory, and antibacterial activities ( Wu et al, 1992 ; Zhao et al, 1995 ; He et al, 2008 ; Yang et al, 2014 ; Xu Y. et al, 2021 ).…”