Diterpenoids from the genus Euphorbia: Structure and biological activity (2013–2019)

Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

“…Their intriguing structures, signicant bioactivities, and elaborate syntheses have attracted considerable attention from related scientic communities. [15][16][17][18][19][20][21][22][23][24][25][26] In this period, several reviews on some specic diterpenoid types or on metabolites from certain Euphorbia plants have included some of these Euphorbia diterpenoids, 17,[27][28][29][30][31][32][33] but none has provided a complete and in-depth view of this topic. In this context, we intend to provide an extensive coverage of Euphorbia diterpenoids from 2013 to the end of 2021.…”

Cytotoxicity and molecular-docking approach of a new rosane-type diterpenoid from the roots of Euphorbia nematocypha

“…Diterpenoids are the main constituents in plants of the genus Euphorbia ( Xu Y. et al, 2021 ). More than 450 diterpenoids have been isolated from Euphorbia species ( Xu Y. et al, 2021 ), which are considered to be taxonomic markers of this genus ( Min et al, 2021 ).…”

“…Diterpenoids are the main constituents in plants of the genus Euphorbia ( Xu Y. et al, 2021 ). More than 450 diterpenoids have been isolated from Euphorbia species ( Xu Y. et al, 2021 ), which are considered to be taxonomic markers of this genus ( Min et al, 2021 ). Diterpenoids from E. nematocypha have shown anticancer activity and antiproliferative effects against cell lines (HL-60, A549, MCF-7, HeLa, and P388), as well as antivirus, anti-inflammatory, and antibacterial activities ( Wu et al, 1992 ; Zhao et al, 1995 ; He et al, 2008 ; Yang et al, 2014 ; Xu Y. et al, 2021 ).…”

Scandium-Catalyzed Skeleton Conversion of Lathyrane to Lathyranone-Type Euphorbia Diterpenes

“…Most of the Euphorbia specia have long been used for medicinal purposes to treat skin diseases, tumors, and asthma , The phytochemistry of Euphorbia diterpenes thus has made considerable progress, resulting in the isolation and identification of a number of novel skeletons in the past few decades. − …”

“…Until now, Euphorbia diterpenes skeletons have been assigned to nearly 40 types . There are many obvious similarities between them, such as those between jatrophane and lathyrane, lathyrane and myrsinane, premyrsinane and cyclomyrsinane, etc.…”