Diterpenoids

Hanson, James R.

doi:10.1039/a807278g

Cited by 39 publications

(22 citation statements)

References 160 publications

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“…Many new monoterpene structures and synthases have been discovered in recent years. While it is not our purpose to review the many new chemical and genetic discoveries in monoterpenes, sesquiterpenes, and diterpenes, there are excellent reviews available (Grayson, 1998;Fraga, 1999;Hanson, 1999).…”

Section: Mono- Sesqui- and Diterpenoidsmentioning

confidence: 99%

REVIEW: Metabolic Engineering of Isoprenoids

Barkovich

Liao

2001

Metabolic Engineering

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Section: Mono- Sesqui- and Diterpenoidsmentioning

confidence: 99%

REVIEW: Metabolic Engineering of Isoprenoids

Barkovich

Liao

2001

Metabolic Engineering

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“…cyclohexene and cyclohexane, trans-fused decalin ring system. It was observed that the majority of isolated clerodanes have trans-ring fusion (Hanson, 1999). The methyl groups at C8 and C9 are cis to each other [C21-C8-C9-C17 = 54.1 (2) ].…”

Section: Commentmentioning

confidence: 99%

A clerodane diterpenoid fromPulicaria wightiana

et al. 2005

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The structure of the clerodane diterpene C21H30O5, with modest antibacterial activity and isolated from the plant Pulicaria wightiana, was established to be methyl 6α‐hydroxy‐3,13‐clerodadien‐15,16‐olid‐18‐oate. The fused six‐membered rings of the decalin system have sofa and chair conformations. The furanone side chain is in an antiperiplanar conformation. The molecules in the crystal structure are stabilized by an intramolecular O—H·O hydrogen bond and a chain of intermolecular C—H·O interactions.

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“…Labdane diterpenoids are among the most common types of diterpenes isolated from terrestrial higher plants and sponges (Hanson, 1997(Hanson, , 1998(Hanson, , 1999(Hanson, , 2000(Hanson, , 2001Tanaka, et al, 2001). Many of these terpenoids possess significant pharmacological properties, such as cytotoxic, antibacterial, antifungal, antiinflammatory, analgesic, antitumor and antimutagenic (Ahsan et al, 2003;Itokawa & Morita, 1988;Dimas et al, 1998;Kittakoop et al, 2001;Kubo et al 2003;Minami et al, 2002;Miyazawa et al, 1995).…”

Section: Commentmentioning

confidence: 99%