Diterpenoid quinones from the Salvia miltiorrhiza and their lung protective activity

(±)-Salvicatone A: A Pair of C27-Meroterpenoid Enantiomers with Skeletons from the Roots and Rhizomes of Salvia castanea Diels f. tomentosa Stib

“…As of 2011, 773 compounds had been isolated from 134 species . Over the past decade, the continued research of the Salvia genus has led to the discovery of a growing number of structurally novel compounds, including sesquiterpenes, − diterpenoids, − sesterterpenoids, , triterpenoids, − flavonoids, , phenolic acids, , and others, , as well as a small number of uncommon terpenoids have also been reported. − Diterpenoids, as one of the characteristic components of Salvia genus, are prone to undergo ring cleavage, rearrangement, decarboxylation, and dimerization, exhibiting remarkable structural diversity. , Another group of characteristic components in the Salvia genus are phenolic acids, mainly composed of danshensu and caffeic acid units, which form different dimers, trimers, and tetramers . Despite the abundant presence of these two types of compounds in Salvia genus, only a small number of adducts between phenolic acids and diterpenoids, such as Salviprolin A and B, are generally connected by ether or ester bonds rather than C–C bonds.…”