Disuse-driven plasticity in the human thalamus and putamen
Roselyne J. Chauvin,
Dillan J. Newbold,
Ashley N. Nielsen
et al.
Abstract:Cortico-striato-thalamo-cortical loops have been heavily studied because of their importance in movement disorders such as Parkinson’s Disease and tremor. Capturing plasticity effect in this circuit has been mainly successful using animals or using invasive electrophysiology in patients. Given the importance of the striatum and thalamus for motor control and skill learning, the current study leverages on an arm immobilization paradigm in humans with neuroimaging to induce disuse and explore human subcortical m… Show more
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