Disturbance of vascular permeability and the microcirculation during short-term immobilization stress

The impact of immunomodulator compound from the group of substituted thiadiazines on the course of stress reaction

“…Consequently, the effect of severe stress has a dual nature: on the one hand, it is a necessary part of a body's adaptation to various factors of the environment, while on the other hand, it causes changes in lesion tissues and amplifies manifestations of a post-traumatic inflammation [89]. Moreover, it causes a general distress to terminal blood flow, affects the rheological properties of blood, vascular permeability, and the morphology and function of mast cells, similar to the disruptions generated directly in the focal point of inflammation [89,90].…”

“…Moreover, it causes a general distress to terminal blood flow, affects the rheological properties of blood, vascular permeability, and the morphology and function of mast cells, similar to the disruptions generated directly in the focal point of inflammation [89,90].…”