DistSNE: Distributed computing and online visualization of DNA methylation‐based central nervous system tumor classification
Kai Schmid,
Jannik Sehring,
Attila Németh
et al.
Abstract:The current state‐of‐the‐art analysis of central nervous system (CNS) tumors through DNA methylation profiling relies on the tumor classifier developed by Capper and colleagues, which centrally harnesses DNA methylation data provided by users. Here, we present a distributed‐computing‐based approach for CNS tumor classification that achieves a comparable performance to centralized systems while safeguarding privacy. We utilize the t‐distributed neighborhood embedding (t‐SNE) model for dimensionality reduction a… Show more
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