Distribution of vitellogenin in zebrafish (Danio rerio) tissues for biomarker analysis

2, 4-Dichloro-6-nitrophenol, a photonitration product of 2, 4-dichlorophenol, caused anti-androgenic potency in Chinese rare minnows (Gobiocypris rarus)

“…In female fish, VTG is generally synthesized in the liver under the control of estrogen, is released into the circulation, and is then deposited in developing oocytes (Girish et al, 2014). In male fish, plasma VTG usually cannot be expressed; however, it may be activated by artificial estrogens or estrogen-like EDCs (Henry et al, 2009;Zhong et al, 2014). In this study, the plasma VTG level increased in male fish after DCNP exposure, which confirmed that DCNP was acting as a xenoestrogen.…”

Disruption of endocrine function in H295R cell in vitro and in zebrafish in vivo by naphthenic acids

“…Combining in vitro and in vivo assays about steroidogenic disruption of NAs, it can be concluded that NAs cause endocrine disrupting effects via steroidogenic modulation, which might be the possible reason for lesser concentrations of T in blood plasma in previous OSPW studies [13][14][15]. Transcription of VTG gene has been developed as a biomarker for estrogenic pollution [47][48][49]. VTG gene expression could be significantly altered in zebrafish larvae by endocrine disrupting chemicals, such as pesticides, polychlorinated biphenyls (PCBs), bisphenol A [27,52].…”

Ectopic synthesis of vitellogenin in testis and epididymis of estrogen-treated lizard Podarcis sicula

“…In zebrafish males, the 17a-ethinylestradiol induces VTG expression and synthesis in dose-and time-dependent pattern in liver, skin and eye (Zhong et al, 2014). The germ cells of medaka males, treated with E2 or estrogen-like substances, are able to incorporate and accumulate VTG (Kobayashi et al, 2005).…”