Distribution of severity of asthma in childhood

Abstract

Objective: To estimate the distribution of asthma severity in a population-based sample of children from Salvador, Brazil.Methods: An epidemiologically oriented questionnaire (International Study of Asthma and Allergies in Childhood, ISAAC) and a questionnaire based on criteria used in clinical practice (The Global Initiative for Asthma, GINA) were administered simultaneously to 417 children aged 5 to 12 years who reported symptoms of asthma in the past 12 months. According to the ISAAC instrument, children were classified into severe and non-severe asthma, whereas GINA clinical criteria produced four categories of severity: intermittent, mild persistent, moderate persistent and severe asthma.Results: Ninety children reported symptoms indicative of severity according to the ISAAC questionnaire. According to GINA criteria, 143 children had intermittent asthma, 160 mild persistent, 51 moderate and 43 severe asthma. Agreement between the two instruments was 81.3% (kappa = 0.5). Conclusions:Most asthmatic children in the Salvador urban area have persistent asthma. Agreement between epidemiological and clinical classifications of asthma severity was satisfactory.J Pediatr (Rio J). 2010;86(5):417-423: Asthma, severity, questionnaire, child.

Study of urinary leukotriene E4 levels in children with acute asthma

“…Mild was the most prevalent. This distribution of asthma severity in Egypt is consistent with the pattern reported in several countries, as concluded by Chipps et al (2006)9 and Simões et al (2010) 10. Also, Hossny et al (2009)11 confirmed these results in a study of 422 asthmatic children living in Cairo and its suburbs.…”

Characteristics of domestic predictors of persistent bronchial asthma in adolescents and allergic rhinitis in children with a distal occlusion

“…In Spain, the moderate course of allergic rhinitis had 63% of the examined children, which is 12% less than our data, but the hypersensitivity to domestic dust mites was registered with a higher frequency and was equal to 61.9 % [16]. Silvia de Magalhaes Simoes and co-authors showed that 143 (36 %) children of 397 children with bronchial asthma had intermittent course; 160 (40 %) -mild persistent course; 51 (12.8 %) -persistent moderate course and 43 (10.8%) -persistent severe course of the disease [17]. In the same way as in our study the prevalence of allergic rhinitis in children living in Korea or in the Southern Mediterranean region was associated with their place of residence and Dermatophagoides pteronyssinus was the dominant in allergen-induced bronchial asthma [18,19].…”

Evolução clínica e estado nutricional de crianças e adolescentes asmáticos acompanhados em Unidade Básica de Saúde

“…Regarding the clinical diagnosis of disease severity in the 1st consultation, the highest frequency was of intermittent asthma (51.5%), while severe asthma was observed in only 1.4%, a similar rate to that reported in the IV Brazilian Guidelines for Asthma Management, 2006. 25 Simões et al, 29 in the municipality of Salvador, state of Bahia, described a higher prevalence of mild (40%) and severe (10.8%) asthma and lower prevalence of intermittent (36%) and moderate (12.8%) asthma.…”

“…Em relação ao diagnóstico clínico de gravidade da doença na primeira consulta, a maior frequência foi de asma intermitente (51,5%) e grave em apenas 1,4%, o que demonstra uma proporção semelhante à citada na IV Diretrizes Brasileiras para o Manejo da Asma, 2006. 25 Simões et al, 29 no município de Salvador, Bahia, descreveram uma prevalência mais elevada de asma leve (40%) e grave (10,8%) e mais baixa de intermitente (36%) e moderada (12,8%).…”