“…In the overall analysis, we observed a marginal difference in the frequency of this polymorphism among cases and controls, which was not significant after adjustments for other variables of interest. These results are in accordance with the findings observed by other authors (Fan et al, 2010;Lin et al, 2005;Logan et al, 2005). The Glu298Asp polymorphism, in turn, has been associated with risk of ischemic shock (Berger et al, 2007), coronary spasm (Yoshimura et al, 1998), coronary artery disease (Colombo et al, 2003;Hingorani et al, 1999), myocardial infarction (Hibi et al, 1998;Shimasaki et al, 1998) and NAION (Sakai et al, 2007).…”