Distribution of osmoregulatory peptides and neuronal-glial configuration in the hypothalamic magnocellular nuclei of desert rodents

Ouali-Hassenaoui, Saliha; Bendjelloul, Mounira; Dekar, Aicha; Theodosis, Dionysia T.

doi:10.1016/j.crvi.2011.09.001

Cited by 8 publications

(4 citation statements)

References 39 publications

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“…Ouali-Hassenaoui et al produced a detailed histo-cytological study of the brain of G. tarabuli, which, according to their study, exhibits the neuronal, glial and synaptic organization characteristics of the activated hypothalamoneurohypophysial system, suggesting that G. tarabuli represents an interesting model for further studies on neurosecretion under strenuous conditions and morphological plasticity studies. 33 Effect of dehydration versus water-rich diet on brain activity. Benaferi and Benhafri et al estimated the effects of a water-rich diet (WRD) on plasma parameters and on the cellular organization of some osmosensitive nerve centers in Gerbillus tarabuli.…”

Section: G Tarabuli Is An Attractive Rodent Model For Biological Rese...mentioning

confidence: 99%

“…produced a detailed histo-cytological study of the brain of G. tarabuli , which, according to their study, exhibits the neuronal, glial and synaptic organization characteristics of the activated hypothalamo-neurohypophysial system, suggesting that G. tarabuli represents an interesting model for further studies on neurosecretion under strenuous conditions and morphological plasticity studies. 33…”

Section: Introductionmentioning

confidence: 99%

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Advances in research on the biology of the desert rodent Gerbillus tarabuli: a review

et al. 2022

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Selection of the appropriate species and strain of laboratory animals are among the scientist’s major concerns. Tarabul’s gerbil ( Gerbillus tarabuli) is a small, seasonally breeding, desert rodent native to Africa. Despite its unique biological features, which make it an ideal model candidate for biomedical research, only a few reports have used it in research. Hence, the present review aims to provide more data about this species, covering all aspects of its biology, such as taxonomy, morphology, anatomy, ecology, wildlife biology, molecular biology, physiology, neurobiology, genetics, reproduction, development, evolutionary biology, and conservation biology, and covers current progress in exploration of G. tarabuli, discussing its valuable characteristics, which are widely useful for research in various fields. This review paper is destined for biologists, scientists, mammologists, zoologists, academics, and students.

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Section: G Tarabuli Is An Attractive Rodent Model For Biological Rese...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Advances in research on the biology of the desert rodent Gerbillus tarabuli: a review

et al. 2022

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“…The present study reveals that the hypothalamic magnocellular nucleus of the desert rodent Meriones libycus is in a hyperactive state and shows several characteristics favoring neurosecretion. In fact, the hyperactivity of the hypothalamo-neurohypophysial system has been already described in two other gerbillidae rodents (Ouali-Hassenaoui et al 2011). From our immunohistochemical observations, it is obvious that the hypothalamic SON of Meriones is very developed; it has a large medio-lateral extension in the dorso-lateral part of the optic chiasm.…”

Section: Avp and Ot Expressionmentioning

confidence: 81%

“…Many studies on desert rodents showed significant VPergic hyperactivity of the hypothalamo–neurophyseal system. In fact, AVP stores were higher in the neurohypophysis of desert rodents than in laboratory rats; the hypothalamic AVP biosynthesis was enhanced, and the releasable pool of neuropeptide was never exhausted (Bridges and James 1982 ; Ouali-Hassenaoui et al 2011 ). Moreover, during dehydration, AVP is the first hormone to be secreted (Bouby and Fernandes 2003 ).…”

Section: Discussionmentioning

confidence: 99%

Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus

Boumansour

Benhafri

Guillon

et al. 2021

Animal Cells and Systems

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In mammals, plasmatic osmolality needs to be stable, and it is highly related to the hydric state of the animals which depends on the activity of the hypothalamic neurohypophysial system and more particularly by vasopressin secretion. Meriones, a desert rodent, can survive even without drinking for more than one month. The mechanism(s) by which they survive under these conditions remains poorly understood. In this study, we examine the water's deprivation consequences on the: (1) anatomy, morphology, and physiology of the hypothalamic supraoptic nucleus, (2) body mass and plasma electrolytes changes in male desert rodents 'Meriones libycus' subjected to water deprivation for 30 days. The effect of water deprivation was evaluated on the structural and cellular organization of the supraoptic nucleus by morphological observations and immunohistochemical approaches, allowing the labeling of AVP but also oxytocin. Our finding demonstrated that upon water deprivation (1) the body weight decreased and reached a plateau after a month of water restriction. (2) The plasmatic osmolality began to decrease and return to values similar to control animals at day 30. (3) The SON, both in hydrated and water-deprived animals, is highly developed.(4) The AVP labeling in the SON increased upon dehydration at variance with OT. These changes observed in body mass and plasma osmolality reveal an important adaptive process of male Meriones in response to prolonged water deprivation. Overall, this animal represents an interesting model for the study of water body homeostasis and the mechanisms underlying the survival of desert rodents to xeric environments.

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Osmoregulation in Desert-Adapted Mammals

Donald

Pannabecker

2015

Sodium and Water Homeostasis

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Distribution of osmoregulatory peptides and neuronal-glial configuration in the hypothalamic magnocellular nuclei of desert rodents

Cited by 8 publications

References 39 publications

Advances in research on the biology of the desert rodent Gerbillus tarabuli: a review

Advances in research on the biology of the desert rodent Gerbillus tarabuli: a review

Vasopressin and oxytocin expression in hypothalamic supraoptic nucleus and plasma electrolytes changes in water-deprived male Meriones libycus

Osmoregulation in Desert-Adapted Mammals

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