Distribution of ocular biometry in young Chinese eyes: The Anyang University Students Eye Study

Abstract

Purpose To investigate the distribution of ocular biometric parameters and its association to refraction in university students in central China. Methods Ocular biometric parameters including axial length (AL), central corneal thickness (CCT), keratometry power (K), anterior chamber depth (AQD) and lens thickness (LT) were measured by an optical biometry in a cohort of university students. Corneal radius of curvature (CR), lens position (LP), lens power (PBennett), vitreous chamber depth (VCD) and AL to corneal radius ratio (AL/CR) were calculated. Cycloplegic refraction was measured using an autorefractor. Results A total of 7650 undergraduate students participated in this study, with a mean age of 20.0 ± 1.4 years. The following ocular biometric parameters were measured: AL (24.78 ± 1.21 mm), CCT (539.83 ± 33.03 μm), AQD (3.23 ± 0.25 mm), LT (3.47 ± 0.18 mm), CR (7.79 ± 0.27 mm), LP (4.97 ± 0.23 mm), VCD (17.55 ± 1.15 mm), PBennett (25.00 ± 1.07 dioptres) and AL/CR (3.18 ± 0.15). Male subjects were found to have longer AL, thicker CCT, flatter CR, thinner lens, deeper AQD and VCD than female ones. Myopic subjects were found to have longer AL, thinner CCT, steeper CR, thinner and posterior lens, deeper AQD and VCD, lower PBennett and larger AL/CR than emmetropes and hyperopes. Spherical equivalent (SE) showed a negative correlation with AL/CR (r = −0.914), AL (r = −0.755) and VCD (r = −0.751). Conclusions This study provided a range of reference values for the main ocular biometric parameters in young adults and reported their distributions based on gender and refractive status. Our study indicates that SE has a strong correlation with AL/CR ratio, AL and VCD.

Associations between anthropometric indicators and refraction in school-age children during the post-COVID-19 era

“…Fourth, we did not provide ocular biometrics. Given the strong relationship between refraction and ocular biometrics ( 39 ), the association between anthropometric indicators and ocular biometrics should also be considered in further research to explore the complex relationship and mechanisms between anthropometric indicators and refraction.…”

Global metrics on ocular biometry: representative averages and standard deviations across ten countries from four continents

“…Newer studies tended to use optical low-coherence reflectometry, a technique which uses patient fixation and results in longer AL readings. Among the studies reporting lens thickness, one study [ 14 ] had a significantly different lens thickness than the other studies, as it was performed on a non-cataract, college aged population (Table 1 ). Thus, we have provided this study’s results as reference, without including it in our global average and standard deviation calculations for ocular biometry.…”

Axial length and anterior chamber indices in elderly population: Tehran Geriatric Eye Study

“…Anterior chamber depth (ACD), volume (ACV), and angle (ACA) are some of the most important risk factors for glaucoma. Several population-based studies have measured the mean values of AL and other ocular biometric components in different age groups in different populations and have investigated their determinants; however, there are clear discrepancies between their results [2,[13][14][15] . Moreover, to our knowledge, this is the first comprehensive study which has examined these parameters exclusively among elderly population.…”