Distribution of Major Histocompatibility Complex Alleles in Cohorts of Patients with Different Levels of Post-Vaccination Antibodies against Hepatitis B
N. V. Vlasenko,
M. D. Chanyshev,
A. V. Peresadina
et al.
Abstract:Relevance. It is known that the immune response to the administration of immunobiological drugs is variable and depends on the individual characteristics of the organism. Host immunogenetic factors have a significant impact on the effectiveness of vaccination. In this study, the frequencies of alleles of the HLA class I (HLA-A, B, C) and class II genes (HLA-DRB1, DPB1, DQB1) were studied in groups of participants with different levels of antibodies (anti-HBs) after vaccination against viral hepatitis B. Aims o… Show more
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