Distribution of Iridoid Glucosides in Plants from the Genus Lippia (Verbenaceae): An investigation of Lippia alba (Mill.) N.E. Brown

Abstract

The distribution of iridoid glucosides in plants from the genus Lippia (Verbenaceae) is described. In the present work, three known iridoids (theviridoside, mussaenoside and gardoside) were isolated from the roots of L. alba and were confirmed by NMR (1H and 13C) spectroscopic data. This information was combined with previous work on seven other Lippia species (obtained through a literature review) to give a thorough account of the iridoid glucosides currently found in this genus.

HPLC/DAD/ESI-MS Analysis of Non-volatile Constituents of Three Brazilian Chemotypes of Lippia alba (Mill.) N. E. Brown

“…This finding is in good agreement with literature data [5]. Four iridoids, theveside (1), geniposidic acid (2), 8-epi-loganin (3) and mussaenoside (4), were detected in infusions and decoctions of all chemotypes studied, in accord with literature data [6][7][8].…”

A validated HPLC method for the analysis of herbal teas from three chemotypes of Brazilian Lippia alba

“…Identification of the constituents was performed by HPLC-DAD-ESI-MS analysis and/or comparing the retention time, the UV and MS spectra of the peaks from the samples with those of authentic reference samples or data reported in the literature (Alipieva, Kokubun, Taskova, Evstatieva, & Handjieva, 2007;Filho et al, 2007;Hennebelle, Sahpaz, & Bailleul, 2006;Kowalska et al, 2007;Li et al, 2008;Stochmal, Simonet, Macias, & Oleszek, 2001). The purity of the peaks was checked by Diode Array Detector coupled to the HPLC system, comparing the UV spectra of each peak with those of authentic references samples when possible and/or examination of the MS spectra.…”

Chemistry of essential oils of the shrub Lippia alba (Verbenaceae) from Mexico and Costa Rica

“…There are several studies concerning the chemical constituents of L. alba. This species contains iridoids (von Poser et al, 1997;Barbosa et al, 2006;Hennebelle et al, 2006a;Filho et al, 2007;Timóteo et al, 2008), aromatics (phenylethanoid/phenylpropanoid compounds) (Barbosa et al, 2006;Hennebelle et al, 2006b;Timóteo et al, 2008), flavonoids (Hennebelle et al, 2006b), biflavonoids (Barbosa et al, 2005), and triterpenoid saponins (Farias et al, 2010). The L. alba essential oils have been extensively investigated and showed large differences in their compositions.…”