“…Consistent with previous immunocytochemical studies in bone and cementum (Bianco et al, 1993;Chen et al, 1994;, BSP and OPN are found to be preferentially associated with a network of electron-dense, granular, and/or reticular material (the so-called ground substance of mineralized matrices) dispersed among the collagen fibrils throughout the mineralized cementum. Lectin cytochemistry confirms that cementum contains glycosylated proteins as previously shown histochemically (Yamamoto, 1986;Cho and Garant, 1989;Yamamoto and Wakita, 1990;Sasano et al, 1992), and additionally identifies specific sugar moieties associated with these proteins and maps with high resolution their distribution with respect to cells and matrix constituents. The labeling pattern obtained with the lectins Con A, RCA, UEA, and WGA is consistent with the known glycosylation chemistry of collagen, BSP, and OPN.…”