Distribution of dengue cases in the state of Oaxaca, Mexico, during the period 2004–2006

Günther, Jeannette; Ramírez-Palacio, Luis Román; Pérez-Ishiwara, David Guillermo; Salas-Benito, Juan Santiago

doi:10.1016/j.jcv.2009.05.007

Cited by 24 publications

(16 citation statements)

References 32 publications

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“…3 The economic burden of the disease has been estimated in millions of international dollars (i.e., I$514 per ambulatory case and I$1,394 per hospitalized case) 4 and thousands of disability adjusted life years (DALYs; i.e., 427 DALYs/million population). 5 In Mexico, DF is endemic all over the country and presents a year-round transmission.…”

Section: Introductionmentioning

confidence: 99%

Climate Variability and Dengue Fever in Warm and Humid Mexico

Colón‐González

Lake²,

Bentham³

2011

The American Society of Tropical Medicine and Hygiene

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Multiple linear regression models were fitted to look for associations between changes in the incidence rate of dengue fever and climate variability in the warm and humid region of Mexico. Data were collected for 12 Mexican provinces over a 23-year period (January 1985 to December 2007). Our results show that the incidence rate or risk of infection is higher during El Niño events and in the warm and wet season. We provide evidence to show that dengue fever incidence was positively associated with the strength of El Niño and the minimum temperature, especially during the cool and dry season. Our study complements the understanding of dengue fever dynamics in the region and may be useful for the development of early warning systems.

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Section: Introductionmentioning

confidence: 99%

Climate Variability and Dengue Fever in Warm and Humid Mexico

Colón‐González

Lake²,

Bentham³

2011

The American Society of Tropical Medicine and Hygiene

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“…These results are like quite a few studies from India revealing greater male predominance. 21 This greater predominance in males has been attributed to the prolonged outdoor activities that increase chances of mosquito bite. 21 Interestingly, according to Global Health Atlas Gumther J et al, Amedia PA, et al, the reports from Asia are a relative contrast to studies from South America which have found either equal proportion of males and females' dengue cases or a greater proportion of female cases which may be explained and is attributed to the known global regional differences in epidemiological patterns.…”

Section: Resultsmentioning

confidence: 99%

“…21 This greater predominance in males has been attributed to the prolonged outdoor activities that increase chances of mosquito bite. 21 Interestingly, according to Global Health Atlas Gumther J et al, Amedia PA, et al, the reports from Asia are a relative contrast to studies from South America which have found either equal proportion of males and females' dengue cases or a greater proportion of female cases which may be explained and is attributed to the known global regional differences in epidemiological patterns. [21][22][23][24][25] Irrespective of gender differences, there were a total of 35/169 (20.71%) seropositive cases in the age group 10-20 years but the highest number of cases were seen in the age group 41-60 years i.e.…”

Section: Resultsmentioning

confidence: 99%

Dengue IgM antibody sero-status assessment: a current experience in a teaching institution

et al. 2017

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Background: In 2015, Delhi city experienced the worst outbreak of dengue infection since 1996 and our laboratory received a very high number of cases for IgM ELISA testing following clinicians’ referrals. The present study intends to correlate IgM antibody response with duration of fever, platelets counts and ‘with age and gender distribution’ of such cases attending OPDs and subsequently admitted to the medicine and pediatric wards in our tertiary care hospital, New Delhi, albeit, with some useful conclusions and suggestions.Methods: A hospital based observational study was conducted enrolling a total of 500 cases, clinically suspected of DF/DHF/DSS that either reported directly or were referred to Safdarjung Hospital from region in and around Delhi and NCR and subsequently admitted to Emergency Medicine and Paediatrics wards. A total of 500 cases and 50 controls were tested for IgM antibody by ‘IgM antibody capture ELISA (MAC ELISA).Results: Of total 500 serum samples tested, 169 i.e. 33.8% were found to be sero positive. Seropositivity was more among the males 99/169 (58.57%) than the females 70/169 (41.43%). The highest numbers of cases were seen in the age group 41-60 years (46.15%). Amongst seropositive cases, 146 (86.39%) cases had fever of >5 days duration while remaining 23 (13.60%) presented with fever of <5 days. Low platelet count between 20,000-1L cells/mm3 was a feature in all the seropositive cases and statistically it was found significant (p-value 0.001).Conclusions: Detection of IgM specific antibodies by MAC ELISA in cases with high index of clinical suspicion continues to be an effective tool providing a supportive criterion to clinical diagnosis, especially during outbreak periods.

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“…Günther et al [29] also reported the predominance of DF and DHF in children with 11-15-year-old group being the most affected [35]. Knowledge of the age-specific risk of the dengue is critical for rational implementation of dengue vaccines and anti-viral drugs to preschool-aged children to achieve greatest impact of disease burden and mortality.…”

Section: Discussionmentioning

confidence: 99%

Serotyping of Dengue Virus from Deadly Outbreaks of Pakistan

Waqar¹

2016

JHVRV

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Dengue Dengue virus (DENV) belonging to the family Flaviviridae consists of 4 serotypes (DEN-1, 2, 3 & 4) causing severe illnesses like dengue fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Dengue fever has become an emerging disease in Pakistan during the past 5-7 years with an increase in the number of cases every year since 2006. The current study aimed at identifying the serotypes of dengue virus involved in 2011 outbreak of Pakistan. Samples were collected from all provinces of Pakistan. Patients were confirmed in the hospital by antibody captured Enzyme linked immunosorbent assay (ELISA). These ELISA positive serum samples were inoculated on HeLa cell line to raise the viral titer of dengue virus and then RT-PCR was done for serotyping of dengue virus. Initially D1, D2 primers were tried for serotyping of dengue virus but poor results were obtained.Then serotype specific primers were designed having equal fragment length targeting NS1 gene. This approach was successful in serotyping of dengue virus from Pakistani population. On Real time RT-PCR, Dengue virus (DENV) was detected in 43.33% (n=26) patients out of 60 analyzed samples. Among 26 positive cases, 76.9% (n=20) were children and 23.1% (n=6) were adults and 46.1% (n=12) were male and 53.8 % (n=14) were females. ELISA results of 26 PCR positive cases show that 53.8% (n=14) were positive for IgM, 15.4 % (n=4) were positive for IgG and 30.8 % (n=8) were positive for both IgG and IgM. In this study DEN-2 was detected in 13.3% (n=8) patients, DEN-3 was detected in 16.67% (n=10) patients and DEN-2 & DEN-3 coinfection was detected in 13.3% (n=8) patients. We did not detected DEN-1 & DEN-4 in 2011 outbreak of Pakistan in 60 analyzed samples. By this study we can conclude that DEN-2 and DEN-3 were the main serotypes involved in 2011 outbreaks in Pakistan.

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Distribution of dengue cases in the state of Oaxaca, Mexico, during the period 2004–2006

Cited by 24 publications

References 32 publications

Climate Variability and Dengue Fever in Warm and Humid Mexico

Climate Variability and Dengue Fever in Warm and Humid Mexico

Dengue IgM antibody sero-status assessment: a current experience in a teaching institution

Serotyping of Dengue Virus from Deadly Outbreaks of Pakistan

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