Distribution of causes of maternal mortality during delivery and post-partum: results of an African multicentre hospital-based study

Thonneau, Patrick; Matsudai, Tomohiro; Alihonou, E; Souza, José De; Faye, Ousseynou; Moreau, J. C.; Djanhan, Y.; Welffens-Ekra, Christiane; Goyaux, Nathalie

doi:10.1016/j.ejogrb.2003.12.004

Cited by 36 publications

(31 citation statements)

References 15 publications

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“…A OPAS estabelece como alta a mortalidade materna geral acima de 50/100.000 NV 5 . Outra pesquisa, também realizada em Fortaleza, igualmente em hospital terciário, mostrou resultado semelhante 12 . Constatamos existirem altos índices nestas instituições hospitalares por serem centros de referên-cia regional, recebendo maior quantidade de gestantes com doenças 5,[11][12][13][14] .…”

Section: Discussionunclassified

“…Outra pesquisa, também realizada em Fortaleza, igualmente em hospital terciário, mostrou resultado semelhante 12 . Constatamos existirem altos índices nestas instituições hospitalares por serem centros de referên-cia regional, recebendo maior quantidade de gestantes com doenças 5,[11][12][13][14] . Nossa instituição recebe pacientes advindas de outras instituições e, freqüentemente, do interior do estado, principalmente de pequenas cidades vizinhas a Fortaleza, onde inexiste suporte hospitalar terciário.…”

Section: Discussionunclassified

“…Como verificado em outras pesquisas nacionais e internacionais, prevaleceu, entre nós, a hipertensão como primeira causa de morte [11][12][13][14][15][16][17] . A razão específica por esta causa foi de 60,10/ 100.000 NV, próxima do valor de 64,67/100.000 NV observado em instituição terciária similar 12 .…”

Section: Discussionunclassified

“…A razão específica por esta causa foi de 60,10/ 100.000 NV, próxima do valor de 64,67/100.000 NV observado em instituição terciária similar 12 . Em instituição hospitalar de Atlanta, entre 1949 e 2000, Ho et al 18 encontraram razão de mortalidade materna de 92,2/100.000 NV.…”

Section: Discussionunclassified

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Mortalidade materna por hipertensão: índice e análise de suas características em uma maternidade-escola

Bezerra¹,

Júnior²,

Feitosa³

et al. 2005

Rev. Bras. Ginecol. Obstet.

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RESUMOObjetivo: estudar a mortalidade materna por hipertensão na gestação, estimando a razão de mortalidade e o perfil das pacientes que foram a óbito por esta causa. Métodos: estudo retrospectivo dos óbitos maternos devidos à hipertensão ocorridos na Maternidade-Escola Assis Chateaubriand da Universidade Federal do Ceará -MEAC/UFC, no período de 1981 a 2003. Foram avaliadas as razões de mortalidade materna geral (RMM) e específica para hipertensão e, nesta população de hipertensas, os dados epidemiológicos e clínicos. Resultados: registraram-se 296 casos de óbitos maternos e 184.672 nascidos vivos (NV), resultando em RMM de 160,28/100.000 NV. A causa de óbito mais freqüente foi hipertensão (41,2%), com 122 casos e média anual de 5,3 óbitos e RMM para hipertensão de 60,10/100.000 NV. Analisando-se o grupo de mortes por hipertensão verificou-se que a idade materna variou de 13 a 42 anos, com média de 26 anos. A maioria das pacientes originou-se do interior do estado. As mortes aconteceram principalmente nas primeiras 24 horas após a admissão hospitalar (50,9%). Houve predomínio de mortes em primigestas (40,3%) e na faixa entre 31 e 38 semanas (48,2%). A eclâmpsia ocorreu em 73 pacientes (64,1%), sendo mais prevalente durante a gestação (53,4%). Aconteceram 101 óbitos no período puerperal. Houve predomínio de cesárea (62,3%) e de anestesia geral (45,1%). A assistência pré-natal não foi realizada em 61,4% das pacientes. Conclusões: as razões de mortalidade materna geral e por hipertensão foram elevadas, sendo a hipertensão a principal causa de óbito materno em nossa maternidade. PALAVRAS-CHAVE:Hipertensão/mortalidade; Gravidez/metabolismo; Complicações na gravidez; Mortalidade materna; Cuidado pré-natal; Estudos retrospectivos ABSTRACT Purpose: to study maternal mortality caused by hypertension during pregnancy, determining the mortality rate and the profile of those patients. Methods: a retrospective study of maternal mortality caused by hypertension at the Maternidade Escola Assis Chateaubriand of the Universidade Federal do Ceará, from 1981 to 2003. General maternal mortality rate (MMR) and specific maternal mortality rate due to hypertension were evaluated, as well as these patients' epidemiological and clinical data. Results: two hundred and ninety six cases of maternal death and 184,672 of live births were recorded, with a MMR of 160.28/100.000 live births. The most frequent cause of death was hypertension (41.2%); with 122 cases and an annual average of 5.3 deaths, and hypertension MMR of 60.10/100,000 live births. The women's age range varied from 13 to 42 years with an average of 26 years. Most of the patients came from the interior of the state. Deaths occurred predominantly in the first 24 hours after admission to the hospital (50.9%). Deaths were predominant in the first pregnancy (40.3%) and in women with 31 to 38 weeks gestational age (48.2%). Eclampsia occurred in 73 patients (64.1%) and was predominant along the gestational period (53.4%). There were 101 deaths in the puerperium. Cesarean section (6...

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Section: Discussionunclassified

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Mortalidade materna por hipertensão: índice e análise de suas características em uma maternidade-escola

Bezerra¹,

Júnior²,

Feitosa³

et al. 2005

Rev. Bras. Ginecol. Obstet.

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“…ost partum hemorrhage is one of the leading causes of maternal mortality in both the developed and developing world (3,4). Post partum hemorrhage is caused by the loss of blood from the uterus following labor due to decreased uterine tone, retained placenta or placental fragments, as well as lower genital tract trauma (5).…”

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The Comparison of In Vitro Release Methods for the Evaluation of Oxytocin Release from Pluronic® F127 Parenteral Formulations

Chaibva

Walker²

2007

Dissolution Technol.

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The objective of these studies was to develop a discriminatory in vitro release test for assessing formulation factors that may affect oxytocin (OT) release during formulation development studies of a Pluronic® F127 OT in situ gel-forming parenteral dosage form. An appropriate release assessment method should be able to discriminate between the performance of different formulation compositions (1, 2), and this was the primary criterion used for selection of an appropriate test procedure during the test method development process. ANOVA and the difference (f 1 ) and similarity (f 2 ) factors were used to evaluate the discriminatory behavior of different test methods that were investigated in these studies. The in vitro release tests that were investigated included the use of USP Apparatus 1, 2, and 3; a dialysis bag in USP Apparatus 2; and a membrane-less diffusion method. It was concluded that the use of USP Apparatus 3 was best able to discriminate between OT release for the different formulations tested. USP Apparatus 3 was thus considered the most suitable in vitro release test apparatus for studying formulation factors affecting OT release during the development of a parenteral dosage form prepared using Pluronic® F127.

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Older age and higher parity are associated with nonuse of the partograph at Mbarara Regional Referral Hospital, Uganda

Lugobe

Kanyesigye

Mpiima

et al. 2019

Intl J Gynecology & Obste

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Objective:To determine the frequency of partograph use, the proportion of mothers with partographs completed to standard, the completeness of recorded parameters, and factors associated with nonuse at Mbarara Regional Referral Hospital (MRRH), Uganda. Methods:A retrospective review of medical records from mothers admitted to MRRH's postnatal ward between October 2016 and March 2017. Partograph use and whether it had been completed to standard were analyzed.Results: Of 527 study participants, 409 (77.6%) records contained a partograph, of which only 17 (4.2%) had been completed to standard. Parameters most commonly completed to standard were monitoring of cervical dilatation (n=41, 10%), fetal heart rate (n=21, 5.1%), and uterine contractions (n=18, 4.4%). Age older than 30 years (prevalence ratio 1.73; 95% CI, 1.14-2.64) and parity greater than or equal to five (prevalence ratio 1.88; 95% CI, 1.19-2.98) were associated with nonuse of the partograph.Birth outcome was recorded in 98.8% (n=404) of partographs.Conclusion: Appropriate use of the partograph to monitor mothers in labor was extremely low; most common use was to record birth outcomes. Older mothers and those with higher parity were less likely to have their labor monitored using a partograph and should be targeted for partograph interventions.

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Distribution of causes of maternal mortality during delivery and post-partum: results of an African multicentre hospital-based study

Cited by 36 publications

References 15 publications

Mortalidade materna por hipertensão: índice e análise de suas características em uma maternidade-escola

Mortalidade materna por hipertensão: índice e análise de suas características em uma maternidade-escola

The Comparison of In Vitro Release Methods for the Evaluation of Oxytocin Release from Pluronic® F127 Parenteral Formulations

Older age and higher parity are associated with nonuse of the partograph at Mbarara Regional Referral Hospital, Uganda

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