Distribution and growth of hymenolepis diminuta in the rat, hamster and mouse

Turton, J. A.

doi:10.1007/bf00259337

Cited by 16 publications

(4 citation statements)

References 15 publications

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“…This response is correlated with the rejection of the parasite . In spite of the mast cell response in part II of the intestine, which is the parasite's preferred habitat [Turton, 1971], the high number of eosinophils in that part hardly changed after infection. Moreover, the EPO response in the intestinal lumen was not in relation with the eosinophil concentration profile in the intes tinal tissues.…”

Section: Discussionmentioning

confidence: 99%

Influence of an <i>Hymenolepis diminuta</i> Infection on IgE and IgA Bound to Mouse Intestinal Eosinophils

Vorst

Dhont²,

Cesbron³

et al. 1988

Int Arch Allergy Immunol

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Infection of mice with Hymenolepis diminuta, which is an ‘exclusively’ intestinal cestode, affects the number of eosinophils and noneosinophilic cells with IgE or IgA on their surface in the lamina propria. Presence of IgE on eosinophils is basically a primary infection response, while after reinfection the response is primarily characterized by IgA. For IgE- as well as for IgA-bearing eosinophils the response is most abundant in the second quarter of the intestine which is the parasite’s preferred habitat. For non-eosinophilic cells the effect is smaller and limited to the IgE-bearing cells, with the most significant effect in the second quarter of the intestine.

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Section: Discussionmentioning

confidence: 99%

Influence of an <i>Hymenolepis diminuta</i> Infection on IgE and IgA Bound to Mouse Intestinal Eosinophils

Vorst

Dhont²,

Cesbron³

et al. 1988

Int Arch Allergy Immunol

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“…diminuta, i.e. 1045%down the small intestine as found by Turton (1971), for example. By days 7 and 10, a majority of the worms moved posteriorly whereas by day 13 a considerable number of worms had moved anteriorly.…”

Section: Distribution Of Worms and Worm Dry Weightmentioning

confidence: 78%

Immunological and histopathological reactions of the rat against the tapeworm Hymenolepis diminuta and the effects of anti‐thymocyte serum

Hindsbo

Andreassen

Ruitenberg

1982

Parasite Immunology

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Anti-thymocyte-serum (ATS) treated Wistar rats infected with 100 cysticercoids of the rat intestinal cestode Hymenolepis diminuta showed a delayed destrobilation and expulsion of the worms compared with saline-treated infected rats. This result strengthens previous evidence of an immunological nature of the destrobilation and expulsion in lumen-dwelling cestodes--even in their most susceptible hosts. The migration of the worms in the small intestine during the first 20 days of a primary 100-worm infection is described and the anterior migration of the destrobilated worms to the first 10% of the pylorus is emphasized and compared with similar migrations of the nematode Nippostrongylus brasiliensis in the rat. No serum antibodies were detected using passive cutaneous anaphylaxis and the indirect immunofluorescence test, although the thymus-independent areas of the mesenteric lymph nodes showed an increase in pyroninophilic cells. In the small intestine, no response to the tapeworm infection could be detected in pyroninophilic cells and globule leucocytes, but mast cell and eosinophilic cell numbers were increased in the saline-treated infected rats. Although the host responses to H. diminuta are shown to be thymus-dependent, the possibility of thymus-independent activity in the host reactions cannot be ruled out.

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“…Published data show that different vertebrate hosts have variable levels of susceptibility to R. nana and other Hymenolepididae species (Woodland, 1924;Larsh, 1944;Schiller, 1959a, b;Litchford, 1963;De Rycke, 1966;Turton, 1971;Hopkins et al, 1972;Isaak et al, 1977;Murray et al, 1984;van Haeren & de Rycke, 1984;Ishih et al, 1992;Stradowski, 2004). It has been found that non-immunosuppressed M. unguiculatus have low susceptibility to the mouse isolates of R. nana used herein, even when different infection methods are employed.…”

Section: Discussionmentioning

confidence: 99%

Experimental infection and adaptation ofRodentolepis nanato the Mongolian jirdMeriones unguiculatus

Vianna

Melo

2007

J. Helminthol.

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A mouse-derived strain of Rodentolepis ( = Hymenolepis) nana was transferred to the Mongolian jird Meriones unguiculatus. It was found that M. unguiculatus has low susceptibility to R. nana mouse isolates. Likewise, adaptation of the parasite to jird hosts, in the absence of dexamethasone treatment, was not demonstrable, at least during ten-passage trials. Nevertheless, the parasite was able to establish, grow and develop to gravid adults in M. unguiculatus treated daily with dexamethasone. Prepatent periods in dexamethasone-treated jirds in ten-passage series ranged from 10 to 17 days post-infection (DPI), the average being 12 days, and the patent periods lasted from 18 to 30 DPI, with an average of 25 days. The population pattern of faecal egg output in immunosuppressed jirds suggests that under a daily dexamethasone treatment protocol, the parasite is able to maintain egg production as long as treatment is sustained.

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Distribution and growth of hymenolepis diminuta in the rat, hamster and mouse

Cited by 16 publications

References 15 publications

Influence of an <i>Hymenolepis diminuta</i> Infection on IgE and IgA Bound to Mouse Intestinal Eosinophils

Influence of an <i>Hymenolepis diminuta</i> Infection on IgE and IgA Bound to Mouse Intestinal Eosinophils

Immunological and histopathological reactions of the rat against the tapeworm Hymenolepis diminuta and the effects of anti‐thymocyte serum

Experimental infection and adaptation ofRodentolepis nanato the Mongolian jirdMeriones unguiculatus

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