Distribution and Determinants of Eye Size and Shape in Newborn Children: A Magnetic Resonance Imaging Analysis

Abstract

Most newborn Singaporean Asian children are born with prolate eyes. A longitudinal study is required to determine if globe shape at birth influences subsequent refractive changes.

Eye size and shape in newborn children and their relation to axial length and refraction at 3 years

“…We developed an atlas‐based segmentation approach to automatically delineate the left and right eyes from the T2‐weighted image . We manually delineated the eye from one subject's image.…”

“…The length, width, and height described above were the measurements for the internal eye . The term ‘globe’ in this paper refers to the internal surface of the eye …”

“…A summary index of eye shape was given by oblateness, defined as 1 − (axial length/equatorial diameter). Oblateness was determined using both the width and height alternately as the equatorial diameter.…”

“…A prolate eye was defined as oblateness <−0.01, while an oblate eye was defined as oblateness >+0.01. A spherical eye was defined as oblateness between −0.01 and +0.01 . Myopia was defined as spherical equivalent refraction (SER) < −0.5 D.…”

“…We have previously reported on the distribution and variability of ocular dimensions and shape in the normal infant . Evaluating ocular dimensions and shape in infancy provides information on the baseline shape of the globe, before any extrauterine environmental stimuli can have an effect.…”