Distribution and density of cysticerci of Taenia solium by muscle groups and organs in naturally infected local finished pigs in Tanzania

Boa, M.E.; Kassuku, A.A.; Willingham, A. L.; Keyyu, Julius D.; Phiri, Isaac K.; Nansen, P.

doi:10.1016/s0304-4017(02)00037-7

Cited by 69 publications

(72 citation statements)

References 7 publications

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“…Only 18.06% of the cysticercis were located in the heart, tongue and masseter, which are tissues and organs indicated for routine meat inspection for cysticercosis in Brazil. These results corroborate those described by Boa et al (2002), who found that only 10.6% of metacestodes are present in muscles or organs indicated for the search of cysticercosis. As detailed necropsy of pig carcasses followed by the enumeration of cysticerci (considered here as the golden standard) is time-consuming and expensive, it is therefore impractical for traditional inspection and would lead to commercial losses (Gonzalez et al 1990, Pinto et al 2000.…”

Section: Detection Of Circulating Antigen Using Ag-elisasupporting

confidence: 82%

“…Tongue inspection was performed before slaughter and the animals were considered positive for cysticercosis if cyst-like nodules were either seen or felt (Gonzalez et al 1990). All experimentally infected pigs were slaughtered (140 days after infection) and routine meat inspection was performed to determine the presence of cysticerci in predilection sites: masseter muscle, heart and tongue (Boa et al 2002). The inspection was carried out through visual examination and incisions in the muscles and organs.…”

Section: Methodsmentioning

confidence: 99%

“…The inspection was carried out through visual examination and incisions in the muscles and organs. Detailed necropsy was then performed only on the experimentally infected pigs, from which the entire musculature and organs were cut into thin slices of about 0.5cm (Boa et al 2002). The cysticerci were classiϐied as vesicular and non-vesicular based on their macroscopic appearance (Phiri et al 2006).…”

Section: Methodsmentioning

confidence: 99%

“…While the technique is very speciϐic (100%), it is not very sensitive when used on pigs with a low cyst burden (Sciutto et al 1998, Boa et al 2002, Phiri et al 2006, Soares et al 2006). …”

Section: Detection Of Circulating Antigen Using Ag-elisamentioning

confidence: 99%

“…The diagnosis of cysticercosis in pigs can be made by in vivo tongue palpation or meat inspection, which are speciϐic parasitological techniques, but are not very sensitive when used on pigs with a low cyst burden (Sciutto et al 1998, Boa et al 2002. Serological diagnosis methods are important tools for epidemiological studies, as they can be applied to living animals and on a large scale (Gonzales et al 1990) and can help detect cysticercosis in animals with light or recent infections (Pinto et al 2000).…”

Section: Introductionmentioning

confidence: 99%

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Cysticercosis in experimentally and naturally infected pigs: parasitological and immunological diagnosis

et al. 2012

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Our objective was to evaluate the diagnosis of swine cysticercosis by examining "ante mortem" (inspection of the tongue), "post mortem" (inspection and detailed necropsy) and ELISA for research in serum of antibodies (Ab-ELISA) and antigens (Ag-ELISA). Seven (7) pigs were experimentally infected orally with eggs of Taenia solium and another 10 were naturally infected. In the pigs experimentally infected, inspection of the tongue was negative in all animals, in the routine inspection detailed necropsy and cysticercis were identified in all of them. In pigs with heavy natural infection, inspection of the tongue identified cysticerci in two (20%), while at inspection with necropsy the parasites were identified in large quantities in all animals. In ELISA for antibody search (Ab-ELISA) TS-14 recombinant protein was used, and in search for antigen (Ag-ELISA) a monoclonal antibody against this protein. In animals experimentally infected, blood was collected weekly for 140 days. The Ab-ELISA identified an increase in titers of antibody to cysticerci 21 days after infection, and at the end of the experimental period six animals (86%) were positive to the test. The search for circulating antigens (Ag-ELISA) was positive in two pigs 28 to 91 days after infection. All naturally infected pigs were positive for Ag-ELISA and Ab-ELISA. The search for antibodies and antigens by ELISA in serum from 30 pigs of a local farm and without history of cysticercosis was negative. Thus, the use of TS-14 antigen in ELISA test (Ab-ELISA) can be useful for the diagnosis of cysticercosis in pigs with low infection.

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Section: Detection Of Circulating Antigen Using Ag-elisasupporting

confidence: 82%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…While the technique is very speciϐic (100%), it is not very sensitive when used on pigs with a low cyst burden (Sciutto et al 1998, Boa et al 2002, Phiri et al 2006, Soares et al 2006). …”

Section: Detection Of Circulating Antigen Using Ag-elisamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cysticercosis in experimentally and naturally infected pigs: parasitological and immunological diagnosis

et al. 2012

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Taenia solium Cysticercosis/Taeniosis in Europe and Central Asia

Trevisan

Gabriël

Dorny

et al. 2021

Neglected Tropical Diseases

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Epidemiology, clinical manifestations and diagnosis of zoonotic cestode infections: an update

Raether¹,

Hänel²

2003

Parasitology Research

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This paper reviews the literature on zoonotic cestode infections with specific reference to the years 1999-2003. The sources and prevalence of various zoonotic tapeworm infections caused by adult and larval stages of the genera Taenia, Echinococcus, Diphyllobothrium, Hymenolepis and Dipylidium continue to be an important cause of morbidity and mortality, not only in most underdeveloped countries but also in industrialized countries, particularly in rural areas or among immigrant groups from endemic areas. The review gives a detailed report on recent molecular epidemiological studies on the taxonomy and phylogenetic variations in Echinococcus granulosus, immunological tests and imaging techniques used in epidemiological surveys and clinical investigations of important adult and larval tapeworm infections of animals and humans. Larval stages or metacestodes of Taenia solium, Echinococcus spp. and pseudophyllidean tapeworms (Spirometra syn. Diphyllobothrium spp.) may reside in various tissues of their intermediate hosts, including humans. In particular, Cysticercus cellulosae (T. solium) and the larvae of E. granulosus, and E. multilocularis, which are predominantly located in the liver, lungs and central nervous system forming various types of cysts, lead to a complex of systemic diseases such as cysticercosis, cystic echinococcosis and alveolar echinococcosis, respectively. Relatively rare clinical manifestations are seen in the muscles, subcutaneous tissue, spleen, kidneys, bones and body cavities.

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Distribution and density of cysticerci of Taenia solium by muscle groups and organs in naturally infected local finished pigs in Tanzania

Cited by 69 publications

References 7 publications

Cysticercosis in experimentally and naturally infected pigs: parasitological and immunological diagnosis

Cysticercosis in experimentally and naturally infected pigs: parasitological and immunological diagnosis

Taenia solium Cysticercosis/Taeniosis in Europe and Central Asia

Epidemiology, clinical manifestations and diagnosis of zoonotic cestode infections: an update

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