Distribution and course of cortico-respiratory projections for voluntary activation in man

Urbán, Péter; Morgenstern, Michael; Brause, Kai; Wicht, Susanne; Vukurevic, Goran; Kessler, S; Stoeter, P.

doi:10.1007/s00415-002-0702-8

Cited by 32 publications

(22 citation statements)

References 50 publications

(77 reference statements)

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“…The frontal subgyral region and the frontal cortex may correspond closely to the cortical "hotspot" sites identified by electrophysiological studies using the transcranial magnetic stimulation [5,6,11].…”

Section: Discussionmentioning

confidence: 66%

“…Despite these similarities, the underlying musculoskeletal mechanisms and motor patterns of these two coughs differ considerably [29] with different stroke sites resulting in distinct cough impairment. Specific brain lesions that were exclusively investigated in this study; include the frontal lobe, the posterior corona radiate, and the sub-gyral area, which consist of the descending cortico-respiratory projections located within the pyramidal tract [11]. These cortico-respiratory projections are frequently affected in patients with hemiparesis due to stroke [6,7].…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, a recent study by Suntrup-Krueger et al [8] demonstrated the role of specific cortical lesions with impaired RC in stroke patients. Although middle cerebral artery (MCA) [9,10] and capsular infarctions [11] represent major risk factors contributing to a weak diaphragm, the localization of supratentorial regions associated with poor VC is still poorly understood [12]. The brain lesions associated with poor VC are still unknown.…”

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confidence: 99%

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Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

Lee

Lim

Park

et al. 2020

Preprint

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Background: Patients with stroke are known to manifest decreased cough force, which may increase the risk of aspiration. Specific brain lesions have been linked to impaired reflexive cough. However, only a few studies investigated whether specific stroke lesions are associated with impaired voluntary cough. The present study analyzed the effects of stroke lesion on voluntary cough using voxel-based lesion-symptom mapping (VLSM).Methods : In this retrospective cross-sectional study, the peak cough flow was measured in patients who complained of weak cough (n = 39) after supratentorial lesions. Brain lesions were analyzed via magnetic resonance imaging (MRI) at the onset of stroke. These lesions were analyzed using VLSM.Results : The VLSM method with non-parametric mapping revealed that lesions in the sub-gyral frontal lobe, superior longitudinal and posterior corona radiata were related to weak cough flow. Also, lesions in the inferior parietal and temporal lobes, and both superior and mid-temporal gyrus were also associated with weak peak cough flow during voluntary coughing.Conclusions : The present study identified several brain lesions underlying impaired voluntary cough. The results may be useful in predicting those at risk of poor coughing function and may facilitate the prognosis of patients at increased risk of respiratory complications after stroke.

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

Lee

Lim

Park

et al. 2020

Preprint

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“…We hypothesize that diaphragmatic palsy may also be a contributing factor towards the development of pneumonia as an increased incidence of pneumonia has been observed on the hemiparetic side in patients with stroke. [8] This could be due to a weak cough on the side with diaphragmatic palsy. However, large prospective studies are required to validate this.…”

Section: Discussionmentioning

confidence: 99%

Contralateral diaphragmatic palsy in acute stroke: An interesting observation

Kumar¹,

Reddy²,

Prabhakar³

2009

Indian Journal of Critical Care Medicine

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Diaphragmatic palsy in hemiparetic stroke is not well recognized. Further, its implications on stroke outcome have not been studied. Here, we report a patient with left-sided diaphragmatic palsy due to an acute right middle cerebral artery territory infarction. The diagnosis was suspected on finding an elevated dome of the diaphragm on the left side in a routine chest radiograph and was confirmed by finding decreased movements of the left hemidiaphragm on fluoroscopic examination. We hypothesize that this condition is probably under-recognized in clinical practice and its clinical importance not well known. The pathophysiological basis of diaphragmatic palsy in acute stroke and its possible clinical implications are discussed.

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“…Metabolik kontrol sistemlerinin sağlamlığı ile birlikte davranışsal veya istemli solunum kontrolünün harabiyeti farklı solunum şekilleri ortaya çıkarabilir. SVO sonrası istemli göğüs hareketleri vücudun paralitik tarafında azalmıştır (17). Frontal korteks, basal ganglia veya kapsüla interna bölgelerindeki SVO'lar solunum apraksisine neden olabilir.…”

Section: Horlamakunclassified

Sleep related breathing disorders and cerebrovascular diseases

Erdinç¹

2010

Türk Beyin Damar Hast Derg

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ÖZETObstrüktif uyku apne sendromu (OSAS), yüksek prevalanslı ve sıklıkla gözden kaçan, solunumla ilişkili bir uyku bozukluğudur. Uykuda üst hava yollarının gevşeyerek hava yolunu tıkaması sonucu oluşur. Gece boyunca sık uyanmalar, hipoksemi, uykunun bölünmesi ve uyku kalitesinin düşmesi ile izlenir. Şiddetli horlama, tanıklı apneler ve gün içi aşırı uykululuk durumu en önemli semptomlardır. Artmış sempatik aktivite, metabolik ve inflamatuvar markerlar, OSAS ve serebrovasküler hastalıklar arasındaki olası ortak mekanizmayı açıklayabilir. Tedavi seçenekleri için bu mekanizmaların çok iyi bilinmesi gerekir. OSAS'ın erken tanısı ve tedavisi bireyleri serebrovasküler ve diğer komplikasyonlardan koruyabilecektir. SLEEP RELATED BREATHING DISORDERS AND CEREBROVASCULAR DISEASES ABSTRACTObstructive sleep apnea (OSA) is a form of sleep disordered breathing, with a high prevalence rate and is often underdiagnosed. It is characterized by frequent episodes of upper airway collapse during sleep, causing recurrent arousals, intermittent hypoxaemia, sleep fragmentation and poor sleep quality. The common clinical symptoms are heavy snoring, witnessed apnea and daytime hypersomnolence, which would help to identify the affected individuals. Increased sympathetic drive, activation of metabolic and inflammatory markers, and impaired vascular function are some of the proposed mechanisms that could explain the association between OSA and cerebrovascular diseases. Understanding these mechanisms is important for identifying treatment strategies. Increased sympathetic drive, activation of metabolic and inflammatory markers, and impaired vascular function are some of the proposed mechanisms that could explain the association between OSA and cardiovascular diseases. Early recognition and treatment of obstructive sleep apnoea may prevent from adverse health consequences.Yazışma Adresi: Oğuz Osman ERDİNÇ Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, ESKİŞEHİR 1 DERLEME REVIEW Epidemiyoloji OSAS'ın prevalans değerleri kadınlarda %9, erkeklerde %24 şeklinde bildirilmiştir (3). SVO da aynı şekilde sık rastlanılan bir tablodur ve ABD'de üçüncü sıklıkta gelen ölüm nedeni olarak bilinmektedir. Olgu sayısı yılda 700.000'e ulaşmış ve akut nörolojik yakınmalarla başvuran olguların yarısını oluşturmuştur (4). Dünyada ele alındığında, SVO ikinci majör ölüm veya uzun süreli maluliyet nedenidir (5). Obstrüktif apne hipopne indeksine (AHI) göre hafif ve orta şiddetteki OSAS'ın varlığı bile, hastaların SVO için önleyici tedavi almaları gerektiğini göstermektedir (6). HorlamakHorlamak, OSAS'ın en önemli belirtecidir (7). Sık horlama faktörü aynı zamanda, hipertansiyon, kalp hastalıkları, demans ve SVO için oldukça önemlidir (8).Horlamak orta yaşlı erkeklerde ortalama %40-45, aynı yaş grupta kadınlarda %25-30 sıklığındadır. Uykuda meydana gelen SVO olguları horlama ile Solunum ile ilişkili uyku bozuklukları (SUB) içinde en sık rastlanılanı obstrüktif uyku apne sendromudur (OSAS). Klinik semptomlar çok iyi bilinmez veya tanımlanmaz ise...

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Distribution and course of cortico-respiratory projections for voluntary activation in man

Cited by 32 publications

References 50 publications

Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

Contralateral diaphragmatic palsy in acute stroke: An interesting observation

Sleep related breathing disorders and cerebrovascular diseases

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