Distribution and Accumulation of Polychlorinated Biphenyls (PCB), Polycyclic Aromatic Hydrocarbons (PAHs) and Organo-chlorine Residues in the Muscle Tissue of Labeo rohita

Mahboob, Shahid

doi:10.17957/ijab/15.0337

Cited by 4 publications

(4 citation statements)

References 29 publications

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“…Hematological parameters are one of the most important biomarkers to examine the effects of pesticides on health of an organism (Lavanya et al, 2011). Pyrethroid pesticides causes significant alterations in hematological and histopathological parameters of fish (Velisek et al, 2009;Mahboob et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Effects of Sub-Lethal Concentration of Cypermethrin on Histopathological and Hematological Profile of Rohu (Labeo rohita) during Acute Toxicity

Khan¹

2018

IJAB

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The present investigation was designed to understand the lethal effects of Cypermethrin (CYP); an active pyrethroid, a widely used against an extensive range of pests in agriculture. In this study, Rohu (Labeo rohita Hamilton) was subjected to the treatment with three sub-lethal concentrations (0.50, 1.00 and 1.5 ppb) of CYP for a total period of 96 h. The results obtained indicated significant stress in the studied fish due to pesticide intoxication. Pronounced effects of CYP on fish hematology included significant increase (p<0.05) in white blood cells (WBCs), platelets and blood glucose level in treated group compared to control group. Conversely; however, substantial decrease in red blood cells (RBCs), hemoglobin (Hb) level, hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) was noticed among the treated group related to control group (p<0.05). Similarly, the histopathological lesions in the gills of exposed fish included lamellar disorder, disruption of cartilaginous core, epithelial lifting, blood mobbing, damage to secondary lamellae, fusion of secondary gills lamellae, twisting and shortening of secondary gills lamellae and degeneration and atrophy. While liver exhibited dissolution of cell membrane, Pyknosis, blood congestion, necrosis, hyperplasia and vacuolations; intestine was characterized by symptoms like necrosis, hemorrhages, over production of goblet cells in villi, disintegration, fusion and shortening of villi. In summary, we reported marked impacts of CYP on both hematological and histopathological traits of L. rohita. These, findings warrant that the indiscriminate use of CYP significantly increased WBCs, platelets and blood glucose level whereas it decreased RBCs, Hb, HCT, MCV, MCH and MCHC respectively. It also significantly affected the histopathology such as disruption of gills, liver and intestine architecture.

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Section: Discussionmentioning

confidence: 99%

Effects of Sub-Lethal Concentration of Cypermethrin on Histopathological and Hematological Profile of Rohu (Labeo rohita) during Acute Toxicity

Khan¹

2018

IJAB

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“…To understand the exact distribution of PAHs in aquaculture ecosystems, it is necessary to assess their levels in aquaculture organisms 3 since the consumption of polluted fish is an important health hazard to the human population in developed countries. 4 Skin is also an entry route of PAHs due to its high permeation for protein−lipid, and PAHs are accumulated in the fatty tissue of the body. 5 Six PAHs, benzo(a)anthracene (BaA), benzo(b)fluoranthene (BbF), benzo(k)fluoranthene (BkF), benzo(a)pyrene (BaP), dibenzo(a,h)anthracene (DBA), and indeno- (1,2,3-cd)-pyrene (IND), have been classified as probable human carcinogens by the International Agency for Research on Cancer (IARC).…”

Section: ■ Introductionmentioning

confidence: 99%

“…PAHs reaching the aquatic environment can contaminate aquaculture sediments over a long period, and they may be deposited in the fatty tissues of aquatic animals, leading to health hazards for marine life and human beings. To understand the exact distribution of PAHs in aquaculture ecosystems, it is necessary to assess their levels in aquaculture organisms since the consumption of polluted fish is an important health hazard to the human population in developed countries . Skin is also an entry route of PAHs due to its high permeation for protein–lipid, and PAHs are accumulated in the fatty tissue of the body …”

Section: Introductionmentioning

confidence: 99%

Bioaccumulation of Polycyclic Aromatic Hydrocarbons for Forensic Assessment Using Gas Chromatography–Mass Spectrometry

Pastor-Belda

Campillo

Arroyo‐Manzanares

et al. 2019

Chem. Res. Toxicol.

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Polycyclic aromatic hydrocarbons (PAHs) are considered xenobiotics of a potentially carcinogenic nature, being accumulated in the fatty tissue of the body. The objective of this work was the development and validation of a new analytical method to check the bioaccumulation of these toxic compounds in human organs obtained from autopsies. The contaminants were first isolated from the tissues by salt-assisted liquid–liquid extraction in acetonitrile. Because of the low concentrations of these compounds in the human body, a dispersive liquid–liquid microextraction procedure was included. The preconcentrated samples were analyzed by gas chromatography–mass spectrometry to identify the compounds. Principal component analysis was applied to show the natural clustering of forensic samples and orthogonal partial least-squares discriminant analysis to develop a multivariate regression method, which permitted the classification of samples. The quantification limits for the 13 PAHs (acenaphthylene, fluorene, phenanthrene, anthracene, pyrene, benzo(a)anthracene, chrysene, benzo(b)fluoranthene, benzo(k)fluoranthene, benzo(a)pyrene, dibenz(a,h)anthracene, benzo(g,h,i)perylene, and indeno(1,2,3-cd)pyrene) analyzed were in the 0.06–0.44 ng g–1 range, depending on the compound, while the mean intraday relative standard deviation of about 7% demonstrated the high precision of the method. Linearity was verified in the 0.5–200 ng g–1 range, and the enrichment factors were between 55 and 122. The results provided by the analysis of seven different human organs (brain, liver, kidney, lung, heart, spleen, and abdominal fat) from eight autopsies confirmed the PAH-bioaccumulation capacity of human body, fat showing the highest degree of bioaccumulation. The present work is the first study on PAH contamination in different organs obtained from autopsies, being PAH detected in most human samples at values ranged from 0 to 19 ng g–1.

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“…Esse é o caso, por exemplo, das tartarugas verdes (Chelonia mydas), onde foram encontrados seis HPAs em 100% das amostras de fígado desses animais os quais estavam encalhados no Nordeste brasileiro, o fluoreno apresentou os níveis mais elevados, seguido pelo fenantreno (Vilca et al, 2018;Rossi et al, 2023). Vale ressaltar ainda que, apesar dos seres humanos serem raramente afetados diretamente pela contaminação de petróleo, este processo pode ocorrer através da cadeia alimentar e por várias atividades antropogênicas como mineração, transporte de navios, escoamento urbano, fertilizantes agrícolas e combustão incompleta de materiais como madeira, carvão e petróleo (Mahboob et al, 2017;Mahugija e Njale, 2018;Sun et al, 2018;Pastor-Belda et al, 2019).…”

Section: Contaminação Mundial Por Hidrocarbonetos Policíclicos Aromát...unclassified

Avaliação dos efeitos neurotóxicos e antioxidantes do fenantreno em juvenis de Epinephelus marginatus (Perciformes: Serranidae)

Faria

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Distribution and Accumulation of Polychlorinated Biphenyls (PCB), Polycyclic Aromatic Hydrocarbons (PAHs) and Organo-chlorine Residues in the Muscle Tissue of Labeo rohita

Cited by 4 publications

References 29 publications

Effects of Sub-Lethal Concentration of Cypermethrin on Histopathological and Hematological Profile of Rohu (Labeo rohita) during Acute Toxicity

Effects of Sub-Lethal Concentration of Cypermethrin on Histopathological and Hematological Profile of Rohu (Labeo rohita) during Acute Toxicity

Bioaccumulation of Polycyclic Aromatic Hydrocarbons for Forensic Assessment Using Gas Chromatography–Mass Spectrometry

Avaliação dos efeitos neurotóxicos e antioxidantes do fenantreno em juvenis de Epinephelus marginatus (Perciformes: Serranidae)

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