Distributed self in episodic memory: neural correlates of successful retrieval of self-encoded positive and negative personality traits

Fossati, Philippe; Hevenor, Stephanie J.; Lepage, Martín; Graham, Simon J.; Grady, Cheryl L.; Keightley, Michelle; Craik, Fergus I. M.; Mayberg, Helen S.

doi:10.1016/j.neuroimage.2004.03.034

Cited by 156 publications

(127 citation statements)

References 48 publications

Supporting

Mentioning

105

Contrasting

Unclassified

Order By: Relevance

“…The cognitive component of the task (that is 'like me/not like me') engaged the MPFC irrespective of the valence of the trait word, whereas the affective component of the task (that is 'favourable/unfavourable') was resolved in ventral anterior cingulate cortex. 10 Taken together, 7,8,10 the above findings implicate medial frontal, cingulate, parietal cortex and precuneus in tasks that require self-referential processing of personality-trait words.…”

Section: Introductionmentioning

confidence: 83%

“…In a whole brain analysis, significant activations were identified using cluster-based thresholding of statistical images with a height threshold of Z > 2.3 and a (corrected) spatial extent threshold of P < 0.05. 33 Given the findings from earlier neuroimaging studies implicating the right MPFC and vACC, 7,8,10 regions of interest (right MPFC, 8 mm sphere; and vACC, 12 mm sphere) were generated based on the coordinates described by Moran et al 10 Approximate Brodmann's Areas (BA) were identified by transformation of MNI coordinates into Talairach space. 34 (Additional information available at http://www.mrc-cbu.cam.ac.uk/ Imaging.)…”

Section: Visual Stimulation Paradigmmentioning

confidence: 99%

“…Recent functional magnetic resonance imaging (fMRI) [7][8][9][10] and Positron Emission Tomography (PET) 11 studies have identified medial prefrontal (MPFC), parietal and occipital cortex as part of an extended network of brain regions involved in the categorization and recognition of positive and negative personality-trait words processed in a selfreferential manner. For example, increased blood oxygenation level-dependent (BOLD) activity in parietal and occipital regions has been hypothesized to reflect enhanced attentional processes to biologically significant or personally relevant events.…”

Section: Introductionmentioning

confidence: 99%

“…12 In addition, previous work has noted the involvement of the MPFC, premotor, dorsolateral prefrontal cortex and precuneus during tasks that require self reference. 7,8,10,13 Activation in these regions during selfreferential processing may reflect a number of cognitive processes including attention, elaboration, rehearsal and appraisal/evaluation of emotion 14 processes that are targeted in psychotherapy to guide self regulation of emotional experience. 7 Successful recognition of self-encoded personality-trait words has also been shown to reactivate right MPFC, as well as lateral prefrontal, premotor, parietal, anterior cingulate cortex and precuneus.…”

Section: Introductionmentioning

confidence: 99%

“…7 Successful recognition of self-encoded personality-trait words has also been shown to reactivate right MPFC, as well as lateral prefrontal, premotor, parietal, anterior cingulate cortex and precuneus. 8 However, the precise function of MPFC during self-referential processing remains unclear. For example, in a recent fMRI study, Moran et al 10 demonstrated that distinct neural circuits within prefrontal cortex subserve the cognitive and emotional aspects of self-referential processing of personality-trait words.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study

et al. 2007

View full text Add to dashboard Cite

Recent neuropsychological studies in healthy volunteers suggest that antidepressants enhance the processing of positive emotional information. However, the neural substrates underpinning these changes have not been fully elucidated. The current study, therefore, used functional magnetic resonance imaging (fMRI) to map brain systems activated during successful categorization and subsequent recognition of self-referent positive and negative personality characteristics in healthy volunteers following short-term (7 days) repeated administration of the selective noradrenergic reuptake inhibitor reboxetine. Twenty-four healthy volunteers were randomly assigned to 7-day double-blind intervention with reboxetine or placebo. On day 7, neural responses during the categorization and subsequent recognition of positive and negative characteristics were assessed using fMRI. Questionnaires monitoring mood, hostility and anxiety were given before and during this intervention. During categorization, reboxetine was associated with greater activation to positive words, relative to negative words, in left precuneus and right inferior frontal gyrus. By contrast, at subsequent recognition reboxetine was associated with reduced response to positive words, relative to negative words, in left precuneus, anterior cingulate and medial frontal gyrus. These changes in the neural processing of positive and negative words occurred in the absence of significant differences in ratings of mood and anxiety. Such adaptations in the neural processing of emotional information support the hypothesis that antidepressants have early effects on emotional processing in a manner which would be expected to reverse negative biases in depression.

show abstract

Section: Introductionmentioning

confidence: 83%

Section: Visual Stimulation Paradigmmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study

et al. 2007

View full text Add to dashboard Cite

show abstract

Social Cognitive Neuroscience

Lieberman

2010

Handbook of Social Psychology

127

112

View full text Add to dashboard Cite

Social cognitive neuroscience is the study of the processes in the human brain that allow people to understand others, understand themselves, and navigate the social world effectively. Social cognitive neuroscience draws on theories and psychological phenomena from across the social sciences including social cognition, political cognition, behavioral economics, and anthropology. The tools used to study these topics are also wide-ranging including functional magnetic resonance imaging (fMRI), positron emission tomography (PET), transcranial magnetic stimulation (TMS), event-related potentials (ERP), single-cell recording, and neuropsychological lesion techniques.

show abstract