Distinguishing Features of Idiopathic Flushing and Carcinoid Syndrome

Aldrich, Leslie B.; Moattari, Ali Reza; Vinik, Aaron I.

doi:10.1001/archinte.1988.00380120074015

Cited by 38 publications

(1 citation statement)

References 29 publications

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“…Episodic sensation of heat, sweating and flushing may typically last a few minutes, occurring repeatedly throughout the day and night. 3,4 The diagnosis of physiological hypogonadism (menopause) is usually clinical and based on females of climacteric age (around 51 years) presenting with typical symptoms of flushing and sweating. 5 The detection of a low circulating serum estradiol (E 2 ) level combined with elevated serum FSH levels clinches the diagnosis, but is not recommended routinely and this combination of findings may anyway be absent during peri-menopause.…”

Section: Differential Diagnosesmentioning

confidence: 99%

Non-menopausal endocrine and non-endocrine causes of flushing and sweating

2017

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Hot flushes and generalised sweating are relatively common presenting complaints, with hypogonadism an important differential diagnosis in both sexes and menopause being the most typical cause in females of climacteric age. However, a variety of other conditions do need to be carefully considered in respect of eugonadal individuals and also for those hypogonadal ones where properly dosed sex steroid replacement has failed to control flushing and sweating, or where the presentation is atypical. Alternative aetiologies may be immediately obvious from the history and physical examination, but more unusual conditions may require deeper scrutiny. This clinical review elaborates on the non-menopausal endocrine and non-endocrine causes of flushing and sweating, including both common and rarer conditions.

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Section: Differential Diagnosesmentioning

confidence: 99%