Distinguishing different surface interactions for nucleotides adsorbed onto hematite and goethite particle surfaces through ATR-FTIR spectroscopy and DFT calculations

Abstract

Geochemical interfaces can impact the fate and transport of aqueous species in the environment including biomolecules. In this study, we investigate the surface chemistry of adsorbed nucleotides on two mineral...

The Influence of an Isocyanate Structure on a Polyurethane Delivery System for 2′-Deoxycytidine-5′-monophosphate

“…No obvious difference was observed between these three samples and by comparing them with other data on PU materials [36]. The spectrum of the active substance has already been published [37]; it shows a scissoring band of amino groups at 1717 cm −1 , pyrimidine ring vibrations between 1600 and 1529 cm −1 , a C-N stretch at 1491 cm −1 , and three broad bands specific to the phosphate group at 1085, 1002, and 948 cm −1 , where the first two represent the antisymmetric and symmetric stretch of PO 2 − , respectively. within the 1400-1350 cm −1 , 1135-1050 cm −1 , 990-940 cm −1 , and 880-830 cm −1 ranges.…”

“…No obvious difference was observed between these three samples and by comparing them with other data on PU materials [36]. The spectrum of the active substance has already been published [37]; it shows a scissoring band of amino groups at 1717 cm −1 , pyrimidine ring vibrations between 1600 and 1529 cm −1 , a C-N stretch at 1491 cm −1 , and three broad bands specific to the phosphate group at 1085, 1002, and 948 cm −1 , where the first two represent the antisymmetric and symmetric stretch of PO2 -, respectively. The Raman spectra of samples show weak bands at 215.1 cm −1 (str 1) and 279.4 cm −1 (str 3) that correspond to the cleavage of C-C aliphatic bonds, a band between 432.5 cm −1 (str 1) and 433.5 cm −1 (str 2 and str 3) characteristic for several types of alcohols [38], and bands between 596.2 cm −1 (str 2) and 635.7 cm −1 (str 3) attributed to the stretch of C-C alicyclic and aliphatic bonds.…”