Distinctive patterns of sonographic nerve enlargement in Charcot–Marie–Tooth type 1A and hereditary neuropathy with pressure palsies

Enlargement of peripheral nerves in Krabbe disease: The diagnostic value of nerve ultrasound

“…The phenomenon of enlarged peripheral nerves is a known feature in other demyelinating neuropathies . In Charcot–Marie‐Tooth Type 1a (CMT1a), this enlargement is characteristically homogeneous and pronounced, and corresponds to histology .…”

“…High‐resolution ultrasound is an easily available imaging method for peripheral nerves. Its usefulness has already been demonstrated in various studies of hereditary neuropathies …”

Neuropathy associated with immunoglobulin M monoclonal gammopathy: A combined sonographic and nerve conduction study

“…We also assessed whether there were differences between IgM neuropathy and CIDP controls in the distribution of enlargement along the length of nerves. To this end, we deployed nerve ultrasound ratios between sites (cross‐sectional areas [CSA] at known sites of nerve compression vs their proximal nerve segments) and sum‐scores (CSA at multiple sites within a nerve or brachial plexus) …”

“…Using MRI, our group previously showed marked nerve (root) involvement in patients with IgM neuropathy, indicating that pathology is more widespread than the pattern of distal slowing that is suggested by NCS . Nerve ultrasound can be used to study nerve thickening in more detail because it allows assessment of multiple nerves in arms and legs in a short time . We systematically investigated consecutive patients with IgM neuropathy and disease controls to determine whether there is a specific pattern of nerve involvement in this disorder.…”

Spectrum of sonographic changes in hereditary motor and sensory neuropathy with autosomal dominant and X-linked inheritance

“…Как и при других методах ис-следования периферических нервов в ультразвуковой (УЗ) диагностике необходимо выделить количествен-ные характеристики изменения нервов для их исполь-зования в диагностике и, что особенно важно, в диф-ференциальной диагностике. Один из основных УЗ-параметров -площадь поперечного сечения (ППС) нерва, анализ которого был проведен у пациентов с раз-личными типами НМСН (1А, 1B и 2-го), а также при нейропатии со склонностью к параличам от сдавления [2][3][4][5][6][7][8]. При сопоставлении данных УЗИ при НМСН 1А типа с результатами различных элект ро физио-логических параметров периферических нер вов ожи-даемых корреляций выявлено не было [2].…”