Distinct mortality profile in systemic sclerosis: a death certificate study in Rio de Janeiro, Brazil (2006–2015) using a multiple causes of death analysis

Rezende, Renata; Gismondi, Ronaldo Altenburg; Maleh, H.C.; Coelho, Elisa Mendes de Miranda; Vieira, C Sartori; Rosa, Maria Luiza Garcia; Mocarzel, Luís Otávio

doi:10.1007/s10067-017-3951-8

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…[19,20] In the last decade, there have been studies that use this methodology in SAD mortality. [18,[20][21][22][23][24][25][26] However SAD mortality studies in developing countries are scarce, and have not had the impact necessary to impart the importance of SADs as an urgent health issue or to implement health policies designed to reduce mortality. [9,27,28] There are few mortality studies in Cuba that use multiple-cause-of-death analysis, but none of them are related to SADs.…”

Section: Perspectivementioning

confidence: 99%

“…But these sources of information (including specifi c disease registries, primary care databases, administrative databases, archives, cancer registries, mandatory disease-reporting registries and mortality registries) open up opportunities for innovative, effi cient, and cost-effective research to aid decisions made in clinical practice; to plan health services, programming and policies; and to improve patient care and healthcare effi ciency in various settings and geographic regions worldwide. [43] Mortality registries have been used as data sources to research mortality in SAD patients, [12,18,[20][21][22][23][24][25][26] but there are few studies based on these registries despite the fact that they allow for closer examination of population mortality rates, and for inclusion of a greater number of patients over a longer period, which reduces selection bias and sample size problems. They are also more representative of the population than traditional cohort studies conducted among patients who receive specialized care.…”

Section: Perspectivementioning

confidence: 99%

“…[52] In SLE patients, the leading associated causes of death were renal, cardiovascular and infectious, [21] while in SSc patients these causes were infectious, followed by respiratory, cardiovascular and renal. [26] The causes of death most frequently associated with PM/DM were respiratory diseases, infectious diseases and cancer. [20] Use of data from death certifi cates is limited by its failure to permit estimation of indicators of importance such as incidence rates and SMR or for life table analysis.…”

Section: Perspectivementioning

confidence: 99%

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Using Multiple Cause-of-Death Analysis to Estimate Systemic Autoimmune Disease Mortality Burden in Low- and Middle-Income Countries

Hernández-Negrín¹,

Roque-Dapresa²,

Martínez-Morales

et al. 2021

MEDICC Review

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Autoimmune diseases are not always recognized as urgent health issues, despite a worldwide prevalence of 4%-5%. Most estimates come from high-income countries, as low-and middle-income countries face more issues of under-reporting. Despite this and the lack of recognition under current reporting practices, the role these diseases play in mortality must be acknowledged. In particular, considering multiple causes of death as opposed to a single cause of death results in a 1.5-4.2-fold increase in deaths classifi ed as relating to autoimmune diseases, evidence of their share in overall mortality burden, a factor important for patient care and healthcare policy decision making.However, formulating such policies and programs for timely, appropriate diagnoses and care is stymied in low-and middle-income countries by the shortage of methodologically sound studies on mor-tality from systemic autoimmune diseases. This limitation exacerbates inequalities and health gaps among patients in different countries and localities.Multiple cause-of-death methodology has been validated for research on other diseases and demonstrates the mortality burden of these illnesses in countries where traditional methodological approaches, primarily based on prospective cohort studies, are not feasible. Studying mortality from systemic autoimmune diseases by analyzing multiple causes of death with data from national mortality registries is a lowcost alternative to traditional mortality analysis. The objective of this paper is to demonstrate and defend the usefulness of this approach to estimate mortality burden.

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Section: Perspectivementioning

confidence: 99%

Section: Perspectivementioning

confidence: 99%

Section: Perspectivementioning

confidence: 99%

See 1 more Smart Citation

Using Multiple Cause-of-Death Analysis to Estimate Systemic Autoimmune Disease Mortality Burden in Low- and Middle-Income Countries

Hernández-Negrín¹,

Roque-Dapresa²,

Martínez-Morales

et al. 2021

MEDICC Review

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Scoping review of post‐TB pulmonary vascular disease: Proceedings from the 2nd International Post‐Tuberculosis Symposium

Louw,

Van Heerden,

Kalla

et al. 2024

Pulm. circ.

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Tuberculosis (TB) may cause significant long‐term cardiorespiratory complications, of which pulmonary vascular disease is most under‐recognized. TB is rarely listed as a cause of pulmonary hypertension (PH) in most PH guidelines, yet PH may develop at various stages in the time course of TB, from active infection through to the post‐TB period. Predisposing risk factors for the development of PH are likely multifactorial, involving active TB disease and post‐TB lung disease (PTLD), host‐related and environment‐related factors. Moreover, post‐TB PH should likely be classified in Group 3 PH, with the pathogenesis similarly complex and multifactorial as other Group 3 PH causes. Identifying risk factors that predispose to post‐TB PH may aid in developing risk stratification criteria for early identification and referral for confirmatory diagnostic tests. Given that universal screening for PH in TB survivors may be impractical and unfeasible, a targeted screening approach for high‐risk individuals would be sensible. In this scoping review of post‐TB PH, resulting from the proceedings of the 2nd International Post‐Tuberculosis Symposium, we aim to describe the epidemiology, risk factors, and pathophysiology of post‐TB PH. We emphasize diagnosing PH with an alternative set of diagnostic guidelines in resource‐constrained settings where right heart catheterization may not be feasible. Research to describe the burden and distribution of post‐TB PH should be prioritized as there is a current gap in knowledge regarding the prevalence and incidence of post‐TB PH among persons with TB.

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Comorbidity burden in systemic sclerosis: beyond disease-specific complications

et al. 2019

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Distinct mortality profile in systemic sclerosis: a death certificate study in Rio de Janeiro, Brazil (2006–2015) using a multiple causes of death analysis

Cited by 6 publications

References 15 publications

Using Multiple Cause-of-Death Analysis to Estimate Systemic Autoimmune Disease Mortality Burden in Low- and Middle-Income Countries

Using Multiple Cause-of-Death Analysis to Estimate Systemic Autoimmune Disease Mortality Burden in Low- and Middle-Income Countries

Scoping review of post‐TB pulmonary vascular disease: Proceedings from the 2nd International Post‐Tuberculosis Symposium

Comorbidity burden in systemic sclerosis: beyond disease-specific complications

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