2022
DOI: 10.1101/2022.09.05.22279572
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Distinct immune signatures discriminate SARS-CoV-2 vaccine combinations

Abstract: Several vaccines have been found effective against COVID-19, usually administered in homologous regimens, with the same vaccine used for the prime and boost doses. However, recent studies have demonstrated improved protection via heterologous mix-and-match COVID-19 vaccine combinations, and a direct comparison among these regimens is needed to identify the best employment strategies. Here, we show a single-cohort comparison of changes to the humoral and cellular immune compartments following five different COV… Show more

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