Distinct cytokine profiles in late pregnancy in Ugandan people with HIV
Lisa M. Bebell,
Joseph Ngonzi,
Audrey Butler
et al.
Abstract:During pregnancy, multiple immune regulatory mechanisms establish an immune-tolerant environment for the allogeneic fetus, including cellular signals called cytokines that modify immune responses. However, the impact of maternal HIV infection on these responses is incompletely characterized. We analyzed paired maternal and umbilical cord plasma collected during labor from 147 people with HIV taking antiretroviral therapy and 142 HIV-uninfected comparators. Though cytokine concentrations were overall similar be… Show more
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