Distilling Mechanistic Models From Multi-Omics Data
Samantha Erwin,
Joshua R. Fletcher,
Daniel C. Sweeney
et al.
Abstract:High-dimensional multi-omics data sets are increasingly accessible and now routinely being generated as part of medical and biological experiments. However, the ability to infer mechanisms of these data remains low due to the abundance of confounding data. The gap between data generation and interpretation highlights the need for strategies to harmonize and distill complex multi-omics data sets into concise, mechanistic descriptions. To this end, a four step analysis approach for multiomics data is herein demo… Show more
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