Distal neuronal degeneration caused by intracranial lesions.

Rabin, Barry M.; Hebel, D J; Salamon-Murayama, Noriko; Russell, Eric J.

doi:10.2214/ajr.171.1.9648770

Cited by 11 publications

(6 citation statements)

References 1 publication

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“…[5][6][7] In either case, the volume loss does not become visible until at least several months poststroke. [8][9][10][11][12][13] The cerebral peduncle is ideal for assessing postinfarction wallerian degeneration, because its fibers (which are corticofugal) are completely arrayed in parallel, in contrast to most other brain stem areas.…”

mentioning

confidence: 94%

Poststroke Cerebral Peduncular Atrophy Correlates with a Measure of Corticospinal Tract Injury in the Cerebral Hemisphere

Mark

Taub²,

Perkins³

et al. 2008

American Journal of Neuroradiology

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BACKGROUND AND PURPOSE:Methods have not been well developed and tested to predict the extent of remote degeneration in the central nervous system that follows cerebral infarction. We hypothesized that the extent of infarction overlap with the cerebral hemispheric course of the corticospinal tract (CST) on structural MR imaging predicts the extent of ipsilateral cerebral peduncular atrophy in patients with chronic stroke.

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confidence: 94%

Poststroke Cerebral Peduncular Atrophy Correlates with a Measure of Corticospinal Tract Injury in the Cerebral Hemisphere

Mark

Taub²,

Perkins³

et al. 2008

American Journal of Neuroradiology

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“…MR characteristics of the dentate-rubro-olivary pathway in PT cases have been well defined [12][13][14]. HOD usually occurs ipsilateral to the lesion when the lesion is in the brain stem, or contralateral to the lesion when the lesion is in the cerebellum as identified on MR images [1,15]. An interesting feature in our case is that we saw HOD and Wallerian degeneration on different sides.…”

Section: Discussionmentioning

confidence: 55%

Symptomatic palatal tremor is not limited to the activity of guillain-mollaret triangle: A functional magnetic resonance imaging case study

Balaban¹,

Yıldız²,

Öztoprak³

et al. 2012

CMJ

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A 57-year-old man was admitted to our clinic because of speech and swallowing disorder for six months. Palatal tremor and left upper extremity myorhythmia appeared on examination. Magnetic resonance imaging showed hypertrophic olivary degeneration, dentate pathology, Wallerian degeneration, and left parietal cystic encephalomalacia. Functional magnetic resonance imaging study of the brain showed prominent activation on the bilateral globus pallidus and thalamus. We suggest that involuntary movements were introduced by the nuclei of the basal ganglia as a result of olivary dysinhibition. Keywords: Palatal tremor, etiology, mechanism, functional imaging ÖzetElliyedi yaşında erkek hasta altı aydır olan konuşma ve yutma zorluğu nedeni ile kliniğimize başvurdu. Muayenede ritmik palatal tremor ve solda üst ekstremite kaslarında miyoritmi görüldü. Beyin manyetik rezonans görüntüleme çalışmasında oliver çekirdekte hipertrofik dejenerasyon, dentat çekirdek patolojisi, Wallerian dejenerasyon ve sol parietal hemisferde kistik ensefalomalazik alan görüldü. Fonksiyonel manyetik rezonans görüntülemede her iki globus pallidus ve talamusta belirgin aktivasyon tespit edildi. Bu olgu çalışmasından elde edilen sonuçlar; palatal tremorda görülen istemsiz hareketlerin olivar çekirdeğin disinhibisyonu sonucu bazal çekirdekler tarafından oluşturulduğunu düşündürmüştür.Anahtar sözcükler: Palatal tremor, etyoloji, mekanizma, fonksiyonel görüntüleme Geliş tarihi

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“…In comparison with our results, those of previous studies (14,15) showed that FA values remained lower than those of the contralateral side even 1 year after infarction. It has been widely accepted that Wallerian degeneration is associated with the size and location of the infarct (16,17). Small lesions cause only mild nerve fiber damage and are less likely to cause Wallerian degeneration.…”

Section: Discussionmentioning

confidence: 99%

Pontine Infarction: Diffusion-Tensor Imaging of Motor Pathways—A Longitudinal Study

Zhang¹,

Lin²,

Lu³

et al. 2015

Radiology

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Purpose To investigate the dynamic evolution of diffusion indexes in the corticospinal tract (CST) distal to a pontine infarct by using diffusion-tensor imaging, to determine the relationship of these indexes with clinical prognosis, and to explore the structural changes in the motor pathway during recovery. Materials and Methods This study was approved by the institutional ethics committee, and written informed consent was obtained from each participant. Seventeen patients with pontine infarct underwent five diffusion-tensor imaging examinations during a period of 6 months (within 7 days of onset, 14, 30, 90, and 180 after onset). Fractional anisotropic values were measured in the medulla, cerebral peduncle, internal capsule, and centrum semiovale. Fractional anisotropic values of the CST in the ipsilateral side of the infarct were compared with those in the contralateral sides and those in control subjects by using the Student t test and one-way analysis of variance, and their relationships with clinical scores were analyzed by using Pearson correlation analysis. Reconstructions of the CST were performed. Structural changes of the damaged CST were followed up. Results Fractional anisotropic ratios in the CST above the pons decreased significantly compared with those in the contralateral side and those in control subjects within 7 days, on day 14, and on day 30 after onset (P < .001). Fractional anisotropic ratios above the pons on day 14 correlated positively with Fugl-Meyer scores on day 90 (r = 0.771, P < .001) and day 180 (r = 0.730, P = .001). Follow-up diffusion-tensor tractographic images showed regeneration and reorganization of the motor pathways. Conclusion Secondary degeneration of the CST can be detected at diffusion-tensor imaging in the early stages after pontine infarction, which could help predict the motor outcomes. Diffusion-tensor tractography can allow detection of regeneration and reorganization of the motor pathways during recovery.

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Distal neuronal degeneration caused by intracranial lesions.

Cited by 11 publications

References 1 publication

Poststroke Cerebral Peduncular Atrophy Correlates with a Measure of Corticospinal Tract Injury in the Cerebral Hemisphere

Poststroke Cerebral Peduncular Atrophy Correlates with a Measure of Corticospinal Tract Injury in the Cerebral Hemisphere

Symptomatic palatal tremor is not limited to the activity of guillain-mollaret triangle: A functional magnetic resonance imaging case study

Pontine Infarction: Diffusion-Tensor Imaging of Motor Pathways—A Longitudinal Study

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